BMCBI
2006
13 years 11 months ago
2006
Background: The genomic information of a species allows for the genome-scale reconstruction of its metabolic capacity. Such a metabolic reconstruction gives support to metabolic e...
BMCBI
2006
13 years 11 months ago
2006
Background: While biomedical text mining is emerging as an important research area, practical results have proven difficult to achieve. We believe that an important first step tow...
BMCBI
2006
13 years 11 months ago
2006
Background: The identification of statistically overrepresented sequences in the upstream regions of coregulated genes should theoretically permit the identification of potential ...
BMCBI
2006
13 years 11 months ago
2006
Background: The use of exogenous small interfering RNAs (siRNAs) for gene silencing has quickly become a widespread molecular tool providing a powerful means for gene functional s...
BMCBI
2006
13 years 11 months ago
2006
Background: The use of global gene expression profiling to identify sets of genes with similar expression patterns is rapidly becoming a widespread approach for understanding biol...
BMCBI
2006
13 years 11 months ago
2006
Background: Single Nucleotide Polymorphisms (SNPs) are the most common type of polymorphisms found in the human genome. Effective genetic association studies require the identific...
BMCBI
2006
13 years 11 months ago
2006
Background: Comparing related structures and viewing the structures in the context of sequence alignments are important tasks in protein structure-function research. While many pr...
BMCBI
2006
13 years 11 months ago
2006
Background: Modern biology has shifted from "one gene" approaches to methods for genomic-scale analysis like microarray technology, which allow simultaneous measurement ...
BMCBI
2006
13 years 11 months ago
2006
Background: Dynamic modeling of metabolic reaction networks under in vivo conditions is a crucial step in order to obtain a better understanding of the (dis)functioning of living ...
BMCBI
2006
13 years 11 months ago
2006
Background: Predicting residues' contacts using primary amino acid sequence alone is an important task that can guide 3D structure modeling and can verify the quality of the ...