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BMCBI
2006
83views more  BMCBI 2006»
13 years 11 months ago
Bacterial genotyping by 16S rRNA mass cataloging
George W. Jackson, Roger J. McNichols, George E. F...
BMCBI
2006
59views more  BMCBI 2006»
13 years 11 months ago
Novel methods for secondary structure determination using low wavelength (VUV) circular dichroism spectroscopic data
Background: Circular Dichroism (CD) spectroscopy is a widely used method for studying protein structures in solution. Modern synchrotron radiation CD (SRCD) instruments have consi...
Jonathan G. Lees, Andrew J. Miles, Robert W. Janes...
BMCBI
2006
82views more  BMCBI 2006»
13 years 11 months ago
Prediction of a key role of motifs binding E2F and NR2F in down-regulation of numerous genes during the development of the mouse
Background: We previously demonstrated that gene expression profiles during neuronal differentiation in vitro and hippocampal development in vivo were very similar, due to a conse...
Michal Dabrowski, Stein Aerts, Bozena Kaminska
BMCBI
2006
135views more  BMCBI 2006»
13 years 11 months ago
iHAP - integrated haplotype analysis pipeline for characterizing the haplotype structure of genes
Background: The advent of genotype data from large-scale efforts that catalog the genetic variants of different populations have given rise to new avenues for multifactorial disea...
Chun Meng Song, Boon Huat Yeo, Erwin Tantoso, Yuch...
BMCBI
2006
103views more  BMCBI 2006»
13 years 11 months ago
Meta-All: a system for managing metabolic pathway information
Background: Many attempts are being made to understand biological subjects at a systems level. A major resource for these approaches are biological databases, storing manifold inf...
Stephan Weise, Ivo Grosse, Christian Klukas, Dirk ...
BMCBI
2006
103views more  BMCBI 2006»
13 years 11 months ago
Improving missing value imputation of microarray data by using spot quality weights
Background: Microarray technology has become popular for gene expression profiling, and many analysis tools have been developed for data interpretation. Most of these tools requir...
Peter Johansson, Jari Häkkinen
BMCBI
2006
114views more  BMCBI 2006»
13 years 11 months ago
Impact of RNA structure on the prediction of donor and acceptor splice sites
Background: gene identification in genomic DNA sequences by computational methods has become an important task in bioinformatics and computational gene prediction tools are now es...
Sayed-Amir Marashi, Changiz Eslahchi, Hamid Pezesh...
BMCBI
2006
116views more  BMCBI 2006»
13 years 11 months ago
Optimized mixed Markov models for motif identification
Background: Identifying functional elements, such as transcriptional factor binding sites, is a fundamental step in reconstructing gene regulatory networks and remains a challengi...
Weichun Huang, David M. Umbach, Uwe Ohler, Leping ...
BMCBI
2006
129views more  BMCBI 2006»
13 years 11 months ago
Improved alignment quality by combining evolutionary information, predicted secondary structure and self-organizing maps
Background: Protein sequence alignment is one of the basic tools in bioinformatics. Correct alignments are required for a range of tasks including the derivation of phylogenetic t...
Tomas Ohlson, Varun Aggarwal, Arne Elofsson, Rober...