Background: Circular Dichroism (CD) spectroscopy is a widely used method for studying protein structures in solution. Modern synchrotron radiation CD (SRCD) instruments have consi...
Jonathan G. Lees, Andrew J. Miles, Robert W. Janes...
Background: We previously demonstrated that gene expression profiles during neuronal differentiation in vitro and hippocampal development in vivo were very similar, due to a conse...
Background: The advent of genotype data from large-scale efforts that catalog the genetic variants of different populations have given rise to new avenues for multifactorial disea...
Chun Meng Song, Boon Huat Yeo, Erwin Tantoso, Yuch...
Background: Many attempts are being made to understand biological subjects at a systems level. A major resource for these approaches are biological databases, storing manifold inf...
Stephan Weise, Ivo Grosse, Christian Klukas, Dirk ...
Background: Microarray technology has become popular for gene expression profiling, and many analysis tools have been developed for data interpretation. Most of these tools requir...
Background: gene identification in genomic DNA sequences by computational methods has become an important task in bioinformatics and computational gene prediction tools are now es...
Background: Identifying functional elements, such as transcriptional factor binding sites, is a fundamental step in reconstructing gene regulatory networks and remains a challengi...
Weichun Huang, David M. Umbach, Uwe Ohler, Leping ...
Background: Protein sequence alignment is one of the basic tools in bioinformatics. Correct alignments are required for a range of tasks including the derivation of phylogenetic t...
Tomas Ohlson, Varun Aggarwal, Arne Elofsson, Rober...