BMCBI
2008
13 years 10 months ago
2008
Background: Correctly merged data sets that have been independently genotyped can increase statistical power in linkage and association studies. However, alleles from microsatelli...
BMCBI
2008
13 years 10 months ago
2008
Background: Non-biological signal (or noise) has been the bane of microarray analysis. Hybridization effects related to probe-sequence composition and DNA dye-probe interactions h...
BMCBI
2008
13 years 10 months ago
2008
Background: Stimulus Response Experiments to unravel the regulatory properties of metabolic networks are becoming more and more popular. However, their ability to determine enzyme...
BMCBI
2008
13 years 10 months ago
2008
Background: The Structural Descriptor Database (SDDB) is a web-based tool that predicts the function of proteins and functional site positions based on the structural properties o...
BMCBI
2008
13 years 10 months ago
2008
BMCBI
2008
13 years 10 months ago
2008
Background: The epidermal physiology results from a complex regulated homeostasis of keratinocyte proliferation, differentiation and death and is tightly regulated by a specific p...
BMCBI
2008
13 years 10 months ago
2008
BMCBI
2008
13 years 10 months ago
2008
Background: Health and disease of organisms are reflected in their phenotypes. Often, a genetic component to a disease is discovered only after clearly defining its phenotype. In ...
BMCBI
2008
13 years 10 months ago
2008
Background: Choosing the appropriate sample size is an important step in the design of a microarray experiment, and recently methods have been proposed that estimate sample sizes ...
BMCBI
2008
13 years 10 months ago
2008
Background: A new algorithm has been developed for generating conservation profiles that reflect the evolutionary history of the subfamily associated with a query sequence. It is ...