BMCBI
2008
13 years 11 months ago
2008
BMCBI
2008
13 years 11 months ago
2008
Background: Recent approaches for predicting the three-dimensional (3D) structure of proteins such as de novo or fold recognition methods mostly rely on simplified energy potentia...
BMCBI
2008
13 years 11 months ago
2008
Background: Despite significant improvements in computational annotation of genomes, sequences of abnormal, incomplete or incorrectly predicted genes and proteins remain abundant ...
BMCBI
2008
13 years 11 months ago
2008
BMCBI
2008
13 years 11 months ago
2008
Background: With the completion of the Human Genome Project and recent advancements in mutation detection technologies, the volume of data available on genetic variations has rise...
BMCBI
2008
13 years 11 months ago
2008
Background: The combination of gene expression profiling with linkage analysis has become a powerful paradigm for mapping gene expression quantitative trait loci (eQTL). To date, ...
BMCBI
2008
13 years 11 months ago
2008
Background: Transcription factors (TFs) are core functional proteins which play important roles in gene expression control, and they are key factors for gene regulation network co...
BMCBI
2008
13 years 11 months ago
2008
Background: Most microarray experiments are carried out with the purpose of identifying genes whose expression varies in relation with specific conditions or in response to enviro...
BMCBI
2008
13 years 11 months ago
2008
Background: Ubiquitylation plays an important role in regulating protein functions. Recently, experimental methods were developed toward effective identification of ubiquitylation...
BMCBI
2008
13 years 11 months ago
2008
Background: The reconstruction of genetic regulatory networks from microarray gene expression data has been a challenging task in bioinformatics. Various approaches to this proble...