BMCBI
2008
13 years 11 months ago
2008
Background: When predictive survival models are built from high-dimensional data, there are often additional covariates, such as clinical scores, that by all means have to be incl...
BMCBI
2008
13 years 11 months ago
2008
Background: Normalization is essential in dual-labelled microarray data analysis to remove nonbiological variations and systematic biases. Many normalization methods have been use...
BMCBI
2008
2008
PlasmoDraft: a database of Plasmodium falciparum gene function predictions based on postgenomic data
13 years 11 months ago
BMCBI
2008
13 years 11 months ago
2008
Background: We have previously described an approach to predicting the substrate specificity of serine-threonine protein kinases. The method, named Predikin, identifies key conser...
BMCBI
2008
13 years 11 months ago
2008
Background: Millions of single nucleotide polymorphisms have been identified as a result of the human genome project and the rapid advance of high throughput genotyping technology...
BMCBI
2008
2008
Identification of Proteins Secreted by Malaria Parasite into Erythrocyte using SVM and PSSM profiles
13 years 11 months ago
Background: Malaria parasite secretes various proteins in infected RBC for its growth and survival. Thus identification of these secretory proteins is important for developing vac...
BMCBI
2008
13 years 11 months ago
2008
Background: Alternative splicing is an important gene regulation mechanism. It is estimated that about 74% of multi-exon human genes have alternative splicing. High throughput tan...
BMCBI
2008
13 years 11 months ago
2008
Background: Population structure is an important cause leading to inconsistent results in population-based association studies (PBAS) of human diseases. Various statistical method...
BMCBI
2008
13 years 11 months ago
2008
Background: The exponential growth of available biological data has caused bioinformatics to be rapidly moving towards a data-intensive, computational science. As a result, the co...
BMCBI
2008
13 years 11 months ago
2008
Background: In individually dye-balanced microarray designs, each biological sample is hybridized on two different slides, once with Cy3 and once with Cy5. While this strategy ens...