BMCBI
2008
13 years 11 months ago
2008
Background: DNA sequencing is now emerging as an important component in biomedical studies of diseases like cancer. Short-read, highly parallel sequencing instruments are expected...
BMCBI
2008
13 years 11 months ago
2008
Background: Modern proteomes evolved by modification of pre-existing ones. It is extremely important to comparative biology that related proteins be identified as members of the s...
BMCBI
2008
13 years 11 months ago
2008
Background: Genome wide association (GWA) studies are now being widely undertaken aiming to find the link between genetic variations and common diseases. Ideally, a well-powered G...
BMCBI
2008
13 years 11 months ago
2008
BMCBI
2008
13 years 11 months ago
2008
Background: Genomic islands (GIs) are clusters of genes in prokaryotic genomes of probable horizontal origin. GIs are disproportionately associated with microbial adaptations of m...
BMCBI
2008
13 years 11 months ago
2008
Background: Molecular-docking-based virtual screening is an important tool in drug discovery that is used to significantly reduce the number of possible chemical compounds to be i...
BMCBI
2008
13 years 11 months ago
2008
Background: The inference of a genetic network is a problem in which mutual interactions among genes are deduced using time-series of gene expression patterns. While a number of m...
BMCBI
2008
13 years 11 months ago
2008
Background: In the present investigation, we have used an exhaustive metabolite profiling approach to search for biomarkers in recombinant Aspergillus nidulans (mutants that produ...
BMCBI
2008
13 years 11 months ago
2008
Background: Various measures of semantic similarity of terms in bio-ontologies such as the Gene Ontology (GO) have been used to compare gene products. Such measures of similarity ...
BMCBI
2008
13 years 11 months ago
2008
Background: Previous studies comparing quantitative proteomics and microarray data have generally found poor correspondence between the two. We hypothesised that this might in par...