BMCBI
2010
13 years 11 months ago
2010
Background: The analysis of oligonucleotide microarray data in pathogen surveillance and discovery is a challenging task. Target template concentration, nucleic acid integrity, an...
BMCBI
2010
13 years 11 months ago
2010
Background: Time-course microarray experiments can produce useful data which can help in understanding the underlying dynamics of the system. Clustering is an important stage in m...
BMCBI
2010
13 years 11 months ago
2010
Background: The quality of automated gene prediction in microbial organisms has improved steadily over the past decade, but there is still room for improvement. Increasing the num...
BMCBI
2010
13 years 11 months ago
2010
Background: High-throughput automated sequencing has enabled an exponential growth rate of sequencing data. This requires increasing sequence quality and reliability in order to a...
BMCBI
2010
13 years 11 months ago
2010
Background: Gene expression data can be analyzed by summarizing groups of individual gene expression profiles based on GO annotation information. The mean expression profile per g...
BMCBI
2010
13 years 11 months ago
2010
Background: Theme-driven cancer survival studies address whether the expression signature of genes related to a biological process can predict patient survival time. Although this...
BMCBI
2010
13 years 11 months ago
2010
Background: S. cerevisiae, A. thaliana and M. musculus are well-studied organisms in biology and the sequencing of their genomes was completed many years ago. It is still a challe...
BMCBI
2010
13 years 11 months ago
2010
Background: Current commercial high-density oligonucleotide microarrays can hold millions of probe spots on a single microscopic glass slide and are ideal for studying the transcr...
BMCBI
2010
2010
KiDoQ: using docking based energy scores to develop ligand based model for predicting antibacterials
13 years 11 months ago
Background: Identification of novel drug targets and their inhibitors is a major challenge in the field of drug designing and development. Diaminopimelic acid (DAP) pathway is a u...
BMCBI
2010
13 years 11 months ago
2010
Background: Cell volume determination plays a pivotal role in the investigation of the biophysical mechanisms underlying various cellular processes. Whereas light microscopy in pr...