BMCBI
2010
13 years 11 months ago
2010
Background: Combining data from different ethnic populations in a study can increase efficacy of methods designed to identify expression quantitative trait loci (eQTL) compared to...
BMCBI
2010
13 years 11 months ago
2010
Background: High-throughput sequencing technologies, such as the Illumina Genome Analyzer, are powerful new tools for investigating a wide range of biological and medical question...
BMCBI
2010
13 years 11 months ago
2010
Background: Recent developments of high-density SNP chips across a number of species require accurate genetic maps. Despite rapid advances in genome sequence assembly and availabi...
BMCBI
2010
13 years 11 months ago
2010
Background: With advances in high-throughput genomics and proteomics, it is challenging for biologists to deal with large data files and to map their data to annotations in public...
BMCBI
2010
13 years 11 months ago
2010
nd: Although methods based on highly abstract descriptions of protein structures, such as VAST and TOPS, can perform very fast protein structure comparison, the results can lack a...
BMCBI
2010
13 years 11 months ago
2010
The Protein-DNA Interface database (PDIdb) is a repository containing relevant structural information of Protein-DNA complexes solved by X-ray crystallography and available at the...
BMCBI
2010
13 years 11 months ago
2010
Background: Small molecules are of increasing interest for bioinformatics in areas such as metabolomics and drug discovery. The recent release of large open access chemistry datab...
BMCBI
2010
13 years 11 months ago
2010
Background: The analysis of high-throughput screening data sets is an expanding field in bioinformatics. Highthroughput screens by RNAi generate large primary data sets which need...
BMCBI
2010
13 years 11 months ago
2010
