CSB
2005
IEEE
14 years 5 months ago
2005
IEEE
ECOME is an interactive, graph-based model for simulating an evolving, closed consumption web. It demonstrates the fundamental behavior of a global ecosystem over evolutionary tim...
CSB
2005
IEEE
14 years 5 months ago
2005
IEEE
Whole genome duplication (WGD) is followed by massive duplicate deletion that reorganizes gene adjacencies. We compare the deletion patterns and adjacency reorganization following...
CSB
2005
IEEE
14 years 5 months ago
2005
IEEE
This study shows an effective way to explore and visualize the structure-activity relationships (SARs) of flavonoids with antioxidant activity using structure- activity maps (SAMs...
CSB
2005
IEEE
14 years 5 months ago
2005
IEEE
We have used quantitative modeling of signaling networks to show that the mitogen-activated protein kinase cascade — a highly-conserved signaling network in eukaryotes — can f...
CSB
2005
IEEE
14 years 5 months ago
2005
IEEE
We have employed various sequence alignment algorithms and scoring techniques to determine whether current computational tools accurately predict genes that will be off-targeted b...
CSB
2005
IEEE
14 years 5 months ago
2005
IEEE
Traditional phylogenetic tree reconstruction is based on point mutations of a single gene. This approach is hardly suitable for genomes whose genes are almost identical and hardly...
CSB
2005
IEEE
14 years 5 months ago
2005
IEEE
High-throughput scoring of image-based biological assays heavily depends on the extraction of quantitative numerical information from microscopy images. This paper describes how t...
CSB
2005
IEEE
14 years 5 months ago
2005
IEEE
Federal agencies, academia and industries have invested heavily in the development of structural and biothermodynamic data. However, the data are still largely distributed over se...
CSB
2005
IEEE
14 years 5 months ago
2005
IEEE
As the first step toward a multi-scale, hierarchical computational approach for membrane protein structure prediction, the packing of transmembrane helices was modeled at the resi...
CSB
2005
IEEE
14 years 5 months ago
2005
IEEE
In this study we combined the spurious protein interaction data from the Database of Interacting Proteins with the recently published gene expression data of S. cerevisiae grown w...