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NAR
2011
248views Computer Vision» more  NAR 2011»
13 years 2 months ago
NCBI GEO: archive for functional genomics data sets - 10 years on
A decade ago, the Gene Expression Omnibus (GEO) database was established at the National Center for Biotechnology Information (NCBI). The original objective of GEO was to serve as...
Tanya Barrett, Dennis B. Troup, Stephen E. Wilhite...
NAR
2010
159views more  NAR 2010»
13 years 6 months ago
GeneSigDB - a curated database of gene expression signatures
The primary objective of most gene expression studies is the identification of one or more gene signatures; lists of genes whose transcriptional levels are uniquely associated wit...
Aedín C. Culhane, Thomas Schwarzl, Razvan S...
TCBB
2011
13 years 6 months ago
Probabilistic Analysis of Probe Reliability in Differential Gene Expression Studies with Short Oligonucleotide Arrays
— Probe defects are a major source of noise in gene expression studies. While existing approaches detect noisy probes based on external information such as genomic alignments, we...
Leo Lahti, Laura Elo, Tero Aittokallio, Samuel Kas...
BMCBI
2010
178views more  BMCBI 2010»
13 years 11 months ago
Selecting high-dimensional mixed graphical models using minimal AIC or BIC forests
Background: Chow and Liu showed that the maximum likelihood tree for multivariate discrete distributions may be found using a maximum weight spanning tree algorithm, for example K...
David Edwards, Gabriel C. G. de Abreu, Rodrigo Lab...
ACML
2009
Springer
14 years 5 months ago
Automatic Choice of Control Measurements
Abstract. In experimental design, a standard approach for distinguishing experimentally induced effects from unwanted effects is to design control measurements that differ only ...
Gayle Leen, David R. Hardoon, Samuel Kaski