NAR
2011
13 years 2 months ago
2011
The initiation and regulation of transcription in eukaryotes is complex and involves a large number of transcription factors (TFs), which are known to bind to the regulatory regio...
NAR
2011
13 years 2 months ago
2011
Cancer is known to have abundant copy number alterations (CNAs) that greatly contribute to its pathogenesis and progression. Investigation of CNA regions could potentially help id...
NAR
2011
2011
NGSmethDB: a database for next-generation sequencing single-cytosine-resolution DNA methylation data
13 years 2 months ago
Next-generation sequencing (NGS) together with bisulphite conversion allows the generation of whole genome methylation maps at single-cytosine resolution. This allows studying the...
NAR
2011
13 years 2 months ago
2011
Gene duplications are scattered widely throughout the human genome. A single-base difference located in nearly identical duplicated segments may be misjudged as a single nucleotid...
NAR
2011
13 years 2 months ago
2011
Coronary artery disease (CAD) is a complex, multifactorial disease and a leading cause of mortality world wide. Over the past decades, great efforts have been made to elucidate th...
NAR
2011
2011
FragmentStore - a comprehensive database of fragments linking metabolites, toxic molecules and drugs
13 years 2 months ago
Consideration of biomolecules in terms of their molecular building blocks provides valuable new information regarding their synthesis, degradation and similarity. Here, we present...
NAR
2011
13 years 2 months ago
2011
BTO, the BRENDA Tissue Ontology (http://www .BTO.brenda-enzymes.org) represents a comprehensive structured encyclopedia of tissue terms. The project started in 2003 to create a co...
NAR
2011
13 years 2 months ago
2011
The University of California, Santa Cruz Genome Browser (http://genome.ucsc.edu) offers online access to a database of genomic sequence and annotation data for a wide variety of o...
NAR
2011
13 years 2 months ago
2011
dictyBase (http://www.dictybase.org), the model organism database for Dictyostelium, aims to provide the broad biomedical research community with well integrated, high quality dat...
NAR
2011
13 years 2 months ago
2011
The Epigenomics database at the National Center for Biotechnology Information (NCBI) is a new resource that has been created to serve as a comprehensive public resource for whole-...