—Proteins and their interactions govern virtually all cellular processes, such as regulation, signaling, metabolism, and structure. Most experimental findings pertaining to such ...
Background: In a genetic interaction, the phenotype of a double mutant differs from the combined phenotypes of the underlying single mutants. When the single mutants have no growt...
Ping Ye, Brian D. Peyser, Forrest A. Spencer, Joel...
Background: Protein interactions are thought to be largely mediated by interactions between structural domains. Databases such as iPfam relate interactions in protein structures t...
Background: Domains are the basic functional units of proteins. It is believed that protein-protein interactions are realized through domain interactions. Revealing multi-domain c...
Abstract. Lexical variance in biomedical texts poses a challenge to automatic protein relation mining. We therefore propose a new approach that relies only on more general language...
Timur Fayruzov, Martine De Cock, Chris Cornelis, V...
In this paper we show how Constraint Programming (CP) techniques can improve the efficiency and applicability of grid-based algorithms for optimising surface contact between comple...
In this study we combined the spurious protein interaction data from the Database of Interacting Proteins with the recently published gene expression data of S. cerevisiae grown w...
Rogier J. P. van Berlo, Lodewyk F. A. Wessels, S. ...
There is an emerging trend in post-genome biology to study the collection of thousands of protein interaction pairs (protein interactome) derived from high-throughput experiments....