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BMCBI
2007
122views more  BMCBI 2007»
13 years 8 months ago
Dissecting complex transcriptional responses using pathway-level scores based on prior information
Background: The genomewide pattern of changes in mRNA expression measured using DNA microarrays is typically a complex superposition of the response of multiple regulatory pathway...
Harmen J. Bussemaker, Lucas D. Ward, André ...
BMCBI
2005
189views more  BMCBI 2005»
13 years 8 months ago
Quantitative inference of dynamic regulatory pathways via microarray data
Background: The cellular signaling pathway (network) is one of the main topics of organismic investigations. The intracellular interactions between genes in a signaling pathway ar...
Wen-Chieh Chang, Chang-Wei Li, Bor-Sen Chen
NAR
2010
123views more  NAR 2010»
13 years 3 months ago
Xenbase: gene expression and improved integration
Xenbase (www.xenbase.org), the model organism database for Xenopus laevis and X. (Silurana) tropicalis, is the principal centralized resource of genomic, development data and comm...
Jeff B. Bowes, Kevin A. Snyder, Erik Segerdell, Ch...
BMCBI
2005
77views more  BMCBI 2005»
13 years 8 months ago
Ontological visualization of protein-protein interactions
Background: Cellular processes require the interaction of many proteins across several cellular compartments. Determining the collective network of such interactions is an importa...
Harold J. Drabkin, Christopher Hollenbeck, David P...
BMCBI
2008
124views more  BMCBI 2008»
13 years 8 months ago
A relation based measure of semantic similarity for Gene Ontology annotations
Background: Various measures of semantic similarity of terms in bio-ontologies such as the Gene Ontology (GO) have been used to compare gene products. Such measures of similarity ...
Brendan Sheehan, Aaron J. Quigley, Benoit Gaudin, ...