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112
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BMCBI
2010
134views more  BMCBI 2010»
15 years 3 months ago
Localizing triplet periodicity in DNA and cDNA sequences
Background: The protein-coding regions (coding exons) of a DNA sequence exhibit a triplet periodicity (TP) due to fact that coding exons contain a series of three nucleotide codon...
Liya Wang, Lincoln D. Stein
117
Voted
BMCBI
2007
109views more  BMCBI 2007»
15 years 3 months ago
Towards a comprehensive structural coverage of completed genomes: a structural genomics viewpoint
Background: Structural genomics initiatives were established with the aim of solving protein structures on a large-scale. For many initiatives, such as the Protein Structure Initi...
Russell L. Marsden, Tony A. Lewis, Christine A. Or...
BMCBI
2007
135views more  BMCBI 2007»
15 years 3 months ago
LIMPIC: a computational method for the separation of protein MALDI-TOF-MS signals from noise
Background: Mass spectrometry protein profiling is a promising tool for biomarker discovery in clinical proteomics. However, the development of a reliable approach for the separat...
Dante Mantini, Francesca Petrucci, Damiana Pierago...
129
Voted
BMCBI
2007
246views more  BMCBI 2007»
15 years 3 months ago
TomoJ: tomography software for three-dimensional reconstruction in transmission electron microscopy
Background: Transmission electron tomography is an increasingly common three-dimensional electron microscopy approach that can provide new insights into the structure of subcellul...
Cédric Messaoudi, Thomas Boudier, Carlos Os...
123
Voted
BMCBI
2008
112views more  BMCBI 2008»
15 years 3 months ago
A general modeling and visualization tool for comparing different members of a group: application to studying tau-mediated regul
Background: Innumerable biological investigations require comparing collections of molecules, cells or organisms to one another with respect to one or more of their properties. Al...
Arnab Bhattacharya, Sasha Levy, Adria LeBoeuf, Mic...