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» Computation in Gene Networks
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CIBCB
2008
IEEE
13 years 11 months ago
Network motifs in context: An exploration of the evolution of oscillatory dynamics in transcriptional networks
The concept of a network motif--a small set of interacting genes which produce a predictable behaviour at the network level--has attracted considerable attention amongst network an...
Jennifer Hallinan, Anil Wipat
NAR
2010
159views more  NAR 2010»
13 years 4 months ago
GeneSigDB - a curated database of gene expression signatures
The primary objective of most gene expression studies is the identification of one or more gene signatures; lists of genes whose transcriptional levels are uniquely associated wit...
Aedín C. Culhane, Thomas Schwarzl, Razvan S...
BMCBI
2006
126views more  BMCBI 2006»
13 years 9 months ago
A joint model of regulatory and metabolic networks
Background: Gene regulation and metabolic reactions are two primary activities of life. Although many works have been dedicated to study each system, the coupling between them is ...
Chen-Hsiang Yeang, Martin Vingron
BMCBI
2007
148views more  BMCBI 2007»
13 years 9 months ago
Computation of significance scores of unweighted Gene Set Enrichment Analyses
Background: Gene Set Enrichment Analysis (GSEA) is a computational method for the statistical evaluation of sorted lists of genes or proteins. Originally GSEA was developed for in...
Andreas Keller, Christina Backes, Hans-Peter Lenho...
RECOMB
2004
Springer
14 years 10 months ago
Reconstructing reticulate evolution in species: theory and practice
We present new methods for reconstructing reticulate evolution of species due to events such as horizontal transfer or hybrid speciation; both methods are based upon extensions of...
Luay Nakhleh, Tandy Warnow, C. Randal Linder