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» Estimating dynamic models for gene regulation networks
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JCB
2007
198views more  JCB 2007»
13 years 7 months ago
Bayesian Hierarchical Model for Large-Scale Covariance Matrix Estimation
Many bioinformatics problems can implicitly depend on estimating large-scale covariance matrix. The traditional approaches tend to give rise to high variance and low accuracy esti...
Dongxiao Zhu, Alfred O. Hero III
BIBE
2007
IEEE
129views Bioinformatics» more  BIBE 2007»
13 years 11 months ago
Statistial Analysis of nucleosome occupancy and histone modification data
Abstract-- In eukaryotic cells, genomic DNAs wrap around beadlike molecules, called nucleosomes, so as to pack more compactly in the nucleus of the cell. The nucleosome is made up ...
Guo-Cheng Yuan, Jun S. Liu
RECOMB
2010
Springer
13 years 6 months ago
Predicting Nucleosome Positioning Using Multiple Evidence Tracks
Abstract. We describe a probabilistic model, implemented as a dynamic Bayesian network, that can be used to predict nucleosome positioning along a chromosome based on one or more g...
Sheila M. Reynolds, Zhiping Weng, Jeff A. Bilmes, ...
ICML
2009
IEEE
14 years 8 months ago
Dynamic mixed membership blockmodel for evolving networks
In a dynamic social or biological environment, interactions between the underlying actors can undergo large and systematic changes. Each actor can assume multiple roles and their ...
Wenjie Fu, Le Song, Eric P. Xing
RECOMB
2006
Springer
14 years 8 months ago
Genome-Wide Discovery of Modulators of Transcriptional Interactions in Human B Lymphocytes
Abstract. Transcriptional interactions in a cell are modulated by a variety of mechanisms that prevent their representation as pure pairwise interactions between a transcription fa...
Kai Wang, Ilya Nemenman, Nilanjana Banerjee, Adam ...