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BMCBI
2004
154views more  BMCBI 2004»
13 years 9 months ago
Computation of elementary modes: a unifying framework and the new binary approach
Background: Metabolic pathway analysis has been recognized as a central approach to the structural analysis of metabolic networks. The concept of elementary (flux) modes provides ...
Julien Gagneur, Steffen Klamt
BMCBI
2010
126views more  BMCBI 2010»
13 years 9 months ago
Simulation of a Petri net-based Model of the Terpenoid Biosynthesis Pathway
Background: The development and simulation of dynamic models of terpenoid biosynthesis has yielded a systems perspective that provides new insights into how the structure of this ...
Aliah Hazmah Hawari, Zeti-Azura Mohamed-Hussein
CEC
2009
IEEE
14 years 3 months ago
Gene regulation in a particle metabolome
Abstract— The bacterial genome is well understood by biologists. Although its efficiency and adaptability should make it a good model for evolutionary algorithms, the bacterial ...
Simon J. Hickinbotham, Edward Clark, Susan Stepney...
BMCBI
2007
182views more  BMCBI 2007»
13 years 9 months ago
Hybrid elementary flux analysis/nonparametric modeling: application for bioprocess control
Background: The progress in the "-omic" sciences has allowed a deeper knowledge on many biological systems with industrial interest. This knowledge is still rarely used ...
Ana P. Teixeira, Carlos Alves, Paula M. Alves, Man...
BMCBI
2008
189views more  BMCBI 2008»
13 years 9 months ago
AnEnPi: identification and annotation of analogous enzymes
Background: Enzymes are responsible for the catalysis of the biochemical reactions in metabolic pathways. Analogous enzymes are able to catalyze the same reactions, but they prese...
Thomas D. Otto, Ana Carolina R. Guimarães, ...