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» Gene Specific Co-regulation Discovery: An Improved Approach
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BMCBI
2005
81views more  BMCBI 2005»
13 years 7 months ago
Evolutionary sequence analysis of complete eukaryote genomes
Background: Gene duplication and gene loss during the evolution of eukaryotes have hindered attempts to estimate phylogenies and divergence times of species. Although current meth...
Jaime E. Blair, Prachi Shah, S. Blair Hedges
BMCBI
2007
103views more  BMCBI 2007»
13 years 7 months ago
A comprehensive evaluation of SAM, the SAM R-package and a simple modification to improve its performance
Background: The Significance Analysis of Microarrays (SAM) is a popular method for detecting significantly expressed genes and controlling the false discovery rate (FDR). Recently...
Shunpu Zhang
BMCBI
2006
165views more  BMCBI 2006»
13 years 7 months ago
Validation and functional annotation of expression-based clusters based on gene ontology
Background: The biological interpretation of large-scale gene expression data is one of the paramount challenges in current bioinformatics. In particular, placing the results in t...
Ralf Steuer, Peter Humburg, Joachim Selbig
RECOMB
2006
Springer
14 years 8 months ago
Genome-Wide Discovery of Modulators of Transcriptional Interactions in Human B Lymphocytes
Abstract. Transcriptional interactions in a cell are modulated by a variety of mechanisms that prevent their representation as pure pairwise interactions between a transcription fa...
Kai Wang, Ilya Nemenman, Nilanjana Banerjee, Adam ...
TCBB
2010
108views more  TCBB 2010»
13 years 2 months ago
Identification of Full and Partial Class Relevant Genes
Multiclass cancer classification on microarray data has provided the feasibility of cancer diagnosis across all of the common malignancies in parallel. Using multiclass cancer feat...
Zexuan Zhu, Yew-Soon Ong, Jacek M. Zurada