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» Information Management for Genome Level Bioinformatics
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BMCBI
2007
134views more  BMCBI 2007»
13 years 6 months ago
PLAN: a web platform for automating high-throughput BLAST searches and for managing and mining results
Background: BLAST searches are widely used for sequence alignment. The search results are commonly adopted for various functional and comparative genomics tasks such as annotating...
Ji He, Xinbin Dai, Xuechun Zhao
JAMIA
2010
131views more  JAMIA 2010»
13 years 1 months ago
The Enterprise Data Trust at Mayo Clinic: a semantically integrated warehouse of biomedical data
Mayo Clinic's Enterprise Data Trust is a collection of data from patient care, education, research, and administrative transactional systems, organized to support information...
Christopher G. Chute, Scott A. Beck, Thomas B. Fis...
BMCBI
2008
189views more  BMCBI 2008»
13 years 6 months ago
AnEnPi: identification and annotation of analogous enzymes
Background: Enzymes are responsible for the catalysis of the biochemical reactions in metabolic pathways. Analogous enzymes are able to catalyze the same reactions, but they prese...
Thomas D. Otto, Ana Carolina R. Guimarães, ...
BMCBI
2007
126views more  BMCBI 2007»
13 years 6 months ago
Using gene expression data and network topology to detect substantial pathways, clusters and switches during oxygen deprivation
Background: Biochemical investigations over the last decades have elucidated an increasingly complete image of the cellular metabolism. To derive a systems view for the regulation...
Gunnar Schramm, Marc Zapatka, Roland Eils, Rainer ...
BMCBI
2005
89views more  BMCBI 2005»
13 years 6 months ago
Theme discovery from gene lists for identification and viewing of multiple functional groups
Background: High throughput methods of the genome era produce vast amounts of data in the form of gene lists. These lists are large and difficult to interpret without advanced com...
Petri Pehkonen, Garry Wong, Petri Töröne...