Background: Due to the complex and distributed nature of biological research, our current biological knowledge is spread over many redundant annotation databases maintained by man...
Brad T. Sherman, Da Wei Huang, Qina Tan, Yongjian ...
One of the most elaborate and important tasks in biology is the functional annotation of genes. Biologists have developed standardized and structured vocabularies, called bio-onto...
Background: The functional annotation of proteins relies on published information concerning their close and remote homologues in sequence databases. Evidence for remote sequence ...
Charles Richard Bradshaw, Vineeth Surendranath, Bi...
NCBI’s Conserved Domain Database (CDD) is a resource for the annotation of protein sequences with the location of conserved domain footprints, and functional sites inferred from...
Aron Marchler-Bauer, Shennan Lu, John B. Anderson,...
Background: Modern biology has shifted from "one gene" approaches to methods for genomic-scale analysis like microarray technology, which allow simultaneous measurement ...