The analysis of alignments of functionally equivalent proteins can reveal regularities such as correlated positions or residue patterns which are important to ensure a specific f...
Daniel A. Keim, Daniela Oelke, Royal Truman, Klaus...
DNA sequence alignment is a critical step in identifying homology between organisms. The most widely used alignment program, ClustalW, is known to suffer from the local minima pro...
Perry Ridge, Hyrum Carroll, Dan Sneddon, Mark J. C...
An interesting and important, but largely ignored question associated with the ML method is whether there exists only a single maximum likelihood point for a given phylogenetic tr...
This paper discusses an ontology based language modeling text mining approach to the annotation of protein community. Communities appear to play an important role in the functional...
Xiaodan Zhang, Daniel Duanqing Wu, Xiaohua Zhou, X...
Microarray experiments produce gene expression data at such a high speed and volume that it is imperative to use highly specialized computational tools for their analyses. One grou...
Dong-Guk Shin, John Bluis, Yoo Ah Kim, Winfried Kr...
We consider the planted motif search problem, a problem that arises from the need to find transcription factor-binding sites in genomic information. One of the fastest non-exact a...
Proteins are large organic compounds made of amino acids arranged in a linear chain (primary structure). Most proteins fold into unique threedimensional (3D) structures called inte...
Marco Vassura, Luciano Margara, Filippo Medri, Pie...
Clustering algorithms are employed in many bioinformatics tasks, including categorization of protein sequences and analysis of gene-expression data. Although these algorithms are r...