Conformational switching in the secondary structure of RNAs has recently attracted considerable attention, fostered by the discovery of ‘riboswitches’ in living organisms. The...
Cancers in head and neck tends to spread to nearby lymph nodes. Lymph nodes trap the spreading tumor cells but then the tumor starts to grow in these nodes and then spread further...
One of the major challenges in cancer diagnosis from microarray data is to develop robust classification models which are independent of the analysis techniques used and can combi...
In bacterium, genes working in the same pathway or interacting with each other are often organized into operons. Currently, the prediction accuracy for operon/boundary gene pairs ...
Riboswitches are RNA genetic control elements that were recently discovered in living cells. To regulate gene expression, they utilize a unique mechanism whereby small molecules b...
Adaya N. Cohen, Klara Kedem, Michal Shapira, Danny...
The genome projects have provided comprehensive information about the basic building blocks of life. The next challenge is to understand how biological functions emerge from compl...
Samik Ghosh, Preetam Ghosh, Kalyan Basu, Sajal K. ...
One of the major problems in biological data integration is that many data sources are stored as flat-files, with a variety of different layouts. Integrating data from such sour...
Kaushik Sinha, Xuan Zhang, Ruoming Jin, Gagan Agra...
We have recently demonstrated (La et al, Proteins, 58:2005) that sequence fragments approximating the overall familial phylogeny, called phylogenetic motifs (PMs), represent a pro...