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CSB
2005
IEEE
182views Bioinformatics» more  CSB 2005»
14 years 5 months ago
Bacterial Whole Genome Phylogeny Using Proteome Comparison and Optimal Reversal Distance
Traditional phylogenetic tree reconstruction is based on point mutations of a single gene. This approach is hardly suitable for genomes whose genes are almost identical and hardly...
Noppadon Khiripet
CSB
2005
IEEE
139views Bioinformatics» more  CSB 2005»
14 years 5 months ago
Open Microscopy Environment
High-throughput scoring of image-based biological assays heavily depends on the extraction of quantitative numerical information from microscopy images. This paper describes how t...
Ilya G. Goldberg
CSB
2005
IEEE
140views Bioinformatics» more  CSB 2005»
14 years 5 months ago
HIV Structural and Biothermodynamics Databases: a Resource for the Pharmaceutical and Biotechnology Industry
Federal agencies, academia and industries have invested heavily in the development of structural and biothermodynamic data. However, the data are still largely distributed over se...
Talapady N. Bhat, Yadu B. Tewari, Henry Rodriguez,...
CSB
2005
IEEE
124views Bioinformatics» more  CSB 2005»
14 years 5 months ago
Multi-Scale Hierarchical Structure Prediction of Helical Transmembrane Proteins
As the first step toward a multi-scale, hierarchical computational approach for membrane protein structure prediction, the packing of transmembrane helices was modeled at the resi...
Zhong Chen, Ying Xu
CSB
2005
IEEE
139views Bioinformatics» more  CSB 2005»
14 years 5 months ago
Predicting gene function by combining expression and interaction data
In this study we combined the spurious protein interaction data from the Database of Interacting Proteins with the recently published gene expression data of S. cerevisiae grown w...
Rogier J. P. van Berlo, Lodewyk F. A. Wessels, S. ...
CSB
2005
IEEE
155views Bioinformatics» more  CSB 2005»
14 years 5 months ago
Identifying Orthologs: Cycle Splitting on the Breakpoint Graph
Rogier J. P. van Berlo, Lodewyk F. A. Wessels, S. ...
CSB
2005
IEEE
117views Bioinformatics» more  CSB 2005»
14 years 5 months ago
Protein Structure Prediction Using Physical-Based Global Optimization and Knowledge-Guided Fragment Packing
We describe a new method to predict the tertiary structure of new-fold proteins. Our two-phase approach combines the knowledge-based fragmentpacking with the minimization of a phy...
Jinhui Ding, Elizabeth Eskow, Nelson L. Max, Silvi...
CSB
2005
IEEE
124views Bioinformatics» more  CSB 2005»
14 years 5 months ago
Automated Characterization of cellular migration phenomena
Christian Beaudry, Michael E. Berens, Tarek A. El ...
CSB
2005
IEEE
189views Bioinformatics» more  CSB 2005»
14 years 5 months ago
Learning Yeast Gene Functions from Heterogeneous Sources of Data Using Hybrid Weighted Bayesian Networks
We developed a machine learning system for determining gene functions from heterogeneous sources of data sets using a Weighted Naive Bayesian Network (WNB). The knowledge of gene ...
Xutao Deng, Huimin Geng, Hesham H. Ali