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BMCBI
2006
92views more  BMCBI 2006»
14 years 15 days ago
Similarity-based gene detection: using COGs to find evolutionarily-conserved ORFs
Background: Experimental verification of gene products has not kept pace with the rapid growth of microbial sequence information. However, existing annotations of gene locations c...
Bradford C. Powell, Clyde A. Hutchison III
BMCBI
2006
160views more  BMCBI 2006»
14 years 15 days ago
MIMAS: an innovative tool for network-based high density oligonucleotide microarray data management and annotation
Background: The high-density oligonucleotide microarray (GeneChip) is an important tool for molecular biological research aiming at large-scale detection of small nucleotide polym...
Leandro Hermida, Olivier Schaad, Philippe Demougin...
BMCBI
2008
116views more  BMCBI 2008»
14 years 16 days ago
Gene Ontology annotations: what they mean and where they come from
To address the challenges of information integration and retrieval, the computational genomics community increasingly has come to rely on the methodology of creating annotations o...
David P. Hill, Barry Smith, Monica S. McAndrews-Hi...
BMCBI
2008
149views more  BMCBI 2008»
14 years 16 days ago
Accelerating the annotation of sparse named entities by dynamic sentence selection
This paper presents an active learning-like framework for reducing the human effort for making named entity annotations in a corpus. In this framework, the annotation work is perf...
Yoshimasa Tsuruoka, Jun-ichi Tsujii, Sophia Anania...
BMCBI
2008
184views more  BMCBI 2008»
14 years 16 days ago
Integrating protein-protein interactions and text mining for protein function prediction
Background: Functional annotation of proteins remains a challenging task. Currently the scientific literature serves as the main source for yet uncurated functional annotations, b...
Samira Jaeger, Sylvain Gaudan, Ulf Leser, Dietrich...
BMCBI
2008
140views more  BMCBI 2008»
14 years 16 days ago
Corpus annotation for mining biomedical events from literature
Background: Advanced Text Mining (TM) such as semantic enrichment of papers, event or relation extraction, and intelligent Question Answering have increasingly attracted attention...
Jin-Dong Kim, Tomoko Ohta, Jun-ichi Tsujii
BMCBI
2008
129views more  BMCBI 2008»
14 years 16 days ago
Mining phenotypes for gene function prediction
Background: Health and disease of organisms are reflected in their phenotypes. Often, a genetic component to a disease is discovered only after clearly defining its phenotype. In ...
Philip Groth, Bertram Weiss, Hans-Dieter Pohlenz, ...
BMCBI
2007
168views more  BMCBI 2007»
14 years 16 days ago
Automatic extraction of gene ontology annotation and its correlation with clusters in protein networks
Background: Uncovering cellular roles of a protein is a task of tremendous importance and complexity that requires dedicated experimental work as well as often sophisticated data ...
Nikolai Daraselia, Anton Yuryev, Sergei Egorov, Il...
BMCBI
2007
129views more  BMCBI 2007»
14 years 16 days ago
Exploring inconsistencies in genome-wide protein function annotations: a machine learning approach
Background: Incorrectly annotated sequence data are becoming more commonplace as databases increasingly rely on automated techniques for annotation. Hence, there is an urgent need...
Carson M. Andorf, Drena Dobbs, Vasant Honavar
BMCBI
2007
181views more  BMCBI 2007»
14 years 16 days ago
Versatile annotation and publication quality visualization of protein complexes using POLYVIEW-3D
Background: Macromolecular visualization as well as automated structural and functional annotation tools play an increasingly important role in the post-genomic era, contributing ...
Aleksey A. Porollo, Jaroslaw Meller