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BMCBI
2005
126views more  BMCBI 2005»
13 years 7 months ago
Integrative analysis of multiple gene expression profiles with quality-adjusted effect size models
Background: With the explosion of microarray studies, an enormous amount of data is being produced. Systematic integration of gene expression data from different sources increases...
Pingzhao Hu, Celia M. T. Greenwood, Joseph Beyene
BMCBI
2005
162views more  BMCBI 2005»
13 years 7 months ago
Accelerated probabilistic inference of RNA structure evolution
Background: Pairwise stochastic context-free grammars (Pair SCFGs) are powerful tools for evolutionary analysis of RNA, including simultaneous RNA sequence alignment and secondary...
Ian Holmes
BMCBI
2005
116views more  BMCBI 2005»
13 years 7 months ago
WEBnm@: a web application for normal mode analyses of proteins
Background: Normal mode analysis (NMA) has become the method of choice to investigate the slowest motions in macromolecular systems. NMA is especially useful for large biomolecula...
Siv Midtun Hollup, Gisle Sælensminde, Nathal...
BMCBI
2005
112views more  BMCBI 2005»
13 years 7 months ago
Visualization methods for statistical analysis of microarray clusters
Background: The most common method of identifying groups of functionally related genes in microarray data is to apply a clustering algorithm. However, it is impossible to determin...
Matthew A. Hibbs, Nathaniel C. Dirksen, Kai Li, Ol...
BMCBI
2005
109views more  BMCBI 2005»
13 years 7 months ago
Genome comparison without alignment using shortest unique substrings
Background: Sequence comparison by alignment is a fundamental tool of molecular biology. In this paper we show how a number of sequence comparison tasks, including the detection o...
Bernhard Haubold, Nora Pierstorff, Friedrich M&oum...
BMCBI
2005
99views more  BMCBI 2005»
13 years 7 months ago
maxdLoad2 and maxdBrowse: standards-compliant tools for microarray experimental annotation, data management and dissemination
Background: maxdLoad2 is a relational database schema and Java
David Hancock, Michael Wilson, Giles Velarde, Norm...
BMCBI
2005
93views more  BMCBI 2005»
13 years 7 months ago
Identification of novel prognostic markers in cervical intraepithelial neoplasia using LDMAS (LOH Data Management and Analysis S
Background: Detection of Loss of Heterozygosity (LOH) is one of the most common molecular applications in the study of human diseases, in particular cancer. The technique is commo...
Rifat A. Hamoudi, Amina El-Hamidi, Ming-Qing Du
BMCBI
2005
113views more  BMCBI 2005»
13 years 7 months ago
PentaPlot: A software tool for the illustration of genome mosaicism
Background: Dekapentagonal maps depict the phylogenetic relationships of five genomes in a visually appealing diagram and can be viewed as an alternative to a single evolutionary ...
Lutz Hamel, Olga Zhaxybayeva, J. Peter Gogarten