BMCBI
2005
13 years 11 months ago
2005
Background: Estimators of free energies are routinely used to judge the quality of protein structural models. As these estimators still present inaccuracies, they are frequently e...
BMCBI
2005
13 years 11 months ago
2005
BMCBI
2005
13 years 11 months ago
2005
BMCBI
2005
13 years 11 months ago
2005
BMCBI
2005
13 years 11 months ago
2005
Background: The Flaviviridae virus family includes major human and animal pathogens. The RNA dependent RNA polymerase (RdRp) plays a central role in the replication process, and t...
BMCBI
2005
13 years 11 months ago
2005
Background: Protein function is often dependent on subsets of solvent-exposed residues that may exist in a similar three-dimensional configuration in non homologous proteins thus ...
BMCBI
2005
13 years 11 months ago
2005
Background: Accurate and automatic gene finding and structural prediction is a common problem in bioinformatics, and applications need to be capable of handling non-canonical spli...
BMCBI
2005
13 years 11 months ago
2005
Background: Many three-dimensional (3D) images are routinely collected in biomedical research and a number of digital atlases with associated anatomical and other information have...
BMCBI
2005
13 years 11 months ago
2005
Background: The development of high-throughput technologies such as yeast two-hybrid systems and mass spectrometry technologies has made it possible to generate large protein-prot...
BMCBI
2005
13 years 11 months ago
2005
Background: The signal peptide plays an important role in protein targeting and protein translocation in both prokaryotic and eukaryotic cells. This transient, short peptide seque...