BMCBI
2005
13 years 7 months ago
2005
Background: Estimators of free energies are routinely used to judge the quality of protein structural models. As these estimators still present inaccuracies, they are frequently e...
BMCBI
2005
13 years 7 months ago
2005
BMCBI
2005
13 years 7 months ago
2005
BMCBI
2005
13 years 7 months ago
2005
Background: The Flaviviridae virus family includes major human and animal pathogens. The RNA dependent RNA polymerase (RdRp) plays a central role in the replication process, and t...
BMCBI
2005
13 years 7 months ago
2005
Background: Protein function is often dependent on subsets of solvent-exposed residues that may exist in a similar three-dimensional configuration in non homologous proteins thus ...
BMCBI
2005
13 years 7 months ago
2005
Background: Accurate and automatic gene finding and structural prediction is a common problem in bioinformatics, and applications need to be capable of handling non-canonical spli...
BMCBI
2005
13 years 7 months ago
2005
Background: Many three-dimensional (3D) images are routinely collected in biomedical research and a number of digital atlases with associated anatomical and other information have...
BMCBI
2005
13 years 7 months ago
2005
Background: The development of high-throughput technologies such as yeast two-hybrid systems and mass spectrometry technologies has made it possible to generate large protein-prot...
BMCBI
2005
13 years 7 months ago
2005
Background: The signal peptide plays an important role in protein targeting and protein translocation in both prokaryotic and eukaryotic cells. This transient, short peptide seque...