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BMCBI
2005
163views more  BMCBI 2005»
13 years 11 months ago
Alkahest NuclearBLAST: a user-friendly BLAST management and analysis system
Background -: Sequencing of EST and BAC end datasets is no longer limited to large research groups. Drops in per-base pricing have made high throughput sequencing accessible to in...
Stephen E. Diener, Thomas D. Houfek, Sam E. Kalat,...
BMCBI
2005
62views more  BMCBI 2005»
13 years 11 months ago
Differences in codon bias cannot explain differences in translational power among microbes
Background: Translational power is the cellular rate of protein synthesis normalized to the biomass invested in translational machinery. Published data suggest a previously unreco...
Les Dethlefsen, Thomas M. Schmidt
BMCBI
2005
90views more  BMCBI 2005»
13 years 11 months ago
TMB-Hunt: An amino acid composition based method to screen proteomes for beta-barrel transmembrane proteins
Background: Beta-barrel transmembrane (bbtm) proteins are a functionally important and diverse group of proteins expressed in the outer membranes of bacteria (both gram negative a...
Andrew G. Garrow, Alison Agnew, David R. Westhead
BMCBI
2005
91views more  BMCBI 2005»
13 years 11 months ago
COPASAAR - A database for proteomic analysis of single amino acid repeats
Background: Single amino acid repeats make up a significant proportion in all of the proteomes that have currently been determined. They have been shown to be functionally and med...
Daniel P. Depledge, Andrew R. Dalby
BMCBI
2005
108views more  BMCBI 2005»
13 years 11 months ago
SplitTester: software to identify domains responsible for functional divergence in protein family
Background: Many protein families have undergone functional divergence after gene duplications such that current subgroups of the family carry out overlapping but distinct biologi...
Xiang Gao, Kent Vander Velden, Daniel F. Voytas, X...
BMCBI
2005
148views more  BMCBI 2005»
13 years 11 months ago
Nonparametric tests for differential gene expression and interaction effects in multi-factorial microarray experiments
Background: Numerous nonparametric approaches have been proposed in literature to detect differential gene expression in the setting of two user-defined groups. However, there is ...
Xin Gao, Peter X. K. Song
BMCBI
2005
113views more  BMCBI 2005»
13 years 11 months ago
Normal uniform mixture differential gene expression detection for cDNA microarrays
Background: One of the primary tasks in analysing gene expression data is finding genes that are differentially expressed in different samples. Multiple testing issues due to the ...
Nema Dean, Adrian E. Raftery
BMCBI
2005
89views more  BMCBI 2005»
13 years 11 months ago
Comparative analysis of chromatin landscape in regulatory regions of human housekeeping and tissue specific genes
Background: Global regulatory mechanisms involving chromatin assembly and remodelling in the promoter regions of genes is implicated in eukaryotic transcription control especially...
Mythily Ganapathi, Pragya Srivastava, Sushanta Kum...
BMCBI
2005
80views more  BMCBI 2005»
13 years 11 months ago
Sample phenotype clusters in high-density oligonucleotide microarray data sets are revealed using Isomap, a nonlinear algorithm
Background: Life processes are determined by the organism's genetic profile and multiple environmental variables. However the interaction between these factors is inherently ...
Kevin Dawson, Raymond L. Rodriguez, Wasyl Malyj
BMCBI
2005
134views more  BMCBI 2005»
13 years 11 months ago
Windows .NET Network Distributed Basic Local Alignment Search Toolkit (W.ND-BLAST)
Background: BLAST is one of the most common and useful tools for Genetic Research. This paper describes a software application we have termed Windows .NET Distributed Basic Local ...
Scot E. Dowd, Joaquin Zaragoza, Javier R. Rodrigue...