Sciweavers

BMCBI
2005
124views more  BMCBI 2005»
13 years 11 months ago
Evaluating concentration estimation errors in ELISA microarray experiments
Background: Enzyme-linked immunosorbent assay (ELISA) is a standard immunoassay to estimate a protein's concentration in a sample. Deploying ELISA in a microarray format perm...
Don Simone Daly, Amanda M. White, Susan M. Varnum,...
BMCBI
2005
91views more  BMCBI 2005»
13 years 11 months ago
Providing visualisation support for the analysis of anatomy ontology data
Background: Improvements in technology have been accompanied by the generation of large amounts of complex data. This same technology must be harnessed effectively if the knowledg...
Aba-Sah Dadzie, Albert Burger
BMCBI
2005
98views more  BMCBI 2005»
13 years 11 months ago
Iterative approach to model identification of biological networks
Background: Recent advances in molecular biology techniques provide an opportunity for developing detailed mathematical models of biological processes. An iterative scheme is intr...
Kapil G. Gadkar, Rudiyanto Gunawan, Francis J. Doy...
BMCBI
2005
104views more  BMCBI 2005»
13 years 11 months ago
Scoring functions for transcription factor binding site prediction
Background: Transcription factor binding site (TFBS) prediction is a difficult problem, which requires a good scoring function to discriminate between real binding sites and backg...
Markus T. Friberg, Peter von Rohr, Gaston H. Gonne...
BMCBI
2005
103views more  BMCBI 2005»
13 years 11 months ago
SeqDoC: rapid SNP and mutation detection by direct comparison of DNA sequence chromatograms
Background: This paper describes SeqDoC, a simple, web-based tool to carry out direct comparison of ABI sequence chromatograms. This allows the rapid identification of single nucl...
Mark L. Crowe
BMCBI
2005
133views more  BMCBI 2005»
13 years 11 months ago
Ab initio identification of putative human transcription factor binding sites by comparative genomics
Background: Understanding transcriptional regulation of gene expression is one of the greatest challenges of modern molecular biology. A central role in this mechanism is played b...
Davide Corà, Carl Herrmann, Christoph Diete...
BMCBI
2005
120views more  BMCBI 2005»
13 years 11 months ago
SpectralNET - an application for spectral graph analysis and visualization
Background: Graph theory provides a computational framework for modeling a variety of datasets including those emerging from genomics, proteomics, and chemical genetics. Networks ...
Joshua J. Forman, Paul A. Clemons, Stuart L. Schre...
BMCBI
2005
110views more  BMCBI 2005»
13 years 11 months ago
Discovery of protein-protein interactions using a combination of linguistic, statistical and graphical information
Background: The rapid publication of important research in the biomedical literature makes it increasingly difficult for researchers to keep current with significant work in their...
James W. Cooper, Aaron Kershenbaum
BMCBI
2005
70views more  BMCBI 2005»
13 years 11 months ago
Integrating alternative splicing detection into gene prediction
Background: Alternative splicing (AS) is now considered as a major actor in transcriptome/ proteome diversity and it cannot be neglected in the annotation process of a new genome....
Sylvain Foissac, Thomas Schiex
BMCBI
2005
95views more  BMCBI 2005»
13 years 11 months ago
'PACLIMS': A component LIM system for high-throughput functional genomic analysis
Nicole Donofrio, Ravi Rajagopalon, Douglas E. Brow...