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BMCBI
2006
89views more  BMCBI 2006»
13 years 11 months ago
A joint model for nonparametric functional mapping of longitudinal trajectory and time-to-event
Background: The characterization of the relationship between a longitudinal response process and a time-to-event has been a pressing challenge in biostatistical research. This has...
Min Lin, Rongling Wu
BMCBI
2006
99views more  BMCBI 2006»
13 years 11 months ago
MAGIC-SPP: a database-driven DNA sequence processing package with associated management tools
Background: Processing raw DNA sequence data is an especially challenging task for relatively small laboratories and core facilities that produce as many as 5000 or more DNA seque...
Chun Liang, Feng Sun, Haiming Wang, Junfeng Qu, Ro...
BMCBI
2006
118views more  BMCBI 2006»
13 years 11 months ago
Identification of gene expression patterns using planned linear contrasts
Background: In gene networks, the timing of significant changes in the expression level of each gene may be the most critical information in time course expression profiles. With ...
Hao Li, Constance L. Wood, Yushu Liu, Thomas V. Ge...
BMCBI
2006
153views more  BMCBI 2006»
13 years 11 months ago
Discovery of time-delayed gene regulatory networks based on temporal gene expression profiling
Background: It is one of the ultimate goals for modern biological research to fully elucidate the intricate interplays and the regulations of the molecular determinants that prope...
Xia Li, Shaoqi Rao, Wei Jiang, Chuanxing Li, Yun X...
BMCBI
2006
113views more  BMCBI 2006»
13 years 11 months ago
In silico discovery of human natural antisense transcripts
Background: Several high-throughput searches for ppotential natural antisense transcripts (NATs) have been performed recently, but most of the reports were focused on cis type. A ...
Yuan-Yuan Li, Lei Qin, Zong-Ming Guo, Lei Liu, Hao...
BMCBI
2006
128views more  BMCBI 2006»
13 years 11 months ago
Construction of a nasopharyngeal carcinoma 2D/MS repository with Open Source XML Database - Xindice
Background: Many proteomics initiatives require integration of all information with uniformcriteria from collection of samples and data display to publication of experimental resu...
Feng Li, Maoyu Li, Zhiqiang Xiao, Pengfei Zhang, J...
BMCBI
2006
127views more  BMCBI 2006»
13 years 11 months ago
Exploring supervised and unsupervised methods to detect topics in biomedical text
Background: Topic detection is a task that automatically identifies topics (e.g., "biochemistry" and "protein structure") in scientific articles based on infor...
Minsuk Lee, Weiqing Wang, Hong Yu
BMCBI
2006
172views more  BMCBI 2006»
13 years 11 months ago
BioWarehouse: a bioinformatics database warehouse toolkit
Background: This article addresses the problem of interoperation of heterogeneous bioinformatics databases. Results: We introduce BioWarehouse, an open source toolkit for construc...
Thomas J. Lee, Yannick Pouliot, Valerie Wagner, Pr...
BMCBI
2006
109views more  BMCBI 2006»
13 years 11 months ago
A computational approach to discovering the functions of bacterial phytochromes by analysis of homolog distributions
Background: Phytochromes are photoreceptors, discovered in plants, that control a wide variety of developmental processes. They have also been found in bacteria and fungi, but for...
Tilman Lamparter
BMCBI
2006
122views more  BMCBI 2006»
13 years 11 months ago
A comparison of univariate and multivariate gene selection techniques for classification of cancer datasets
Background: Gene selection is an important step when building predictors of disease state based on gene expression data. Gene selection generally improves performance and identifi...
Carmen Lai, Marcel J. T. Reinders, Laura J. van't ...