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BMCBI
2007
104views more  BMCBI 2007»
14 years 14 days ago
Using contextual and lexical features to restructure and validate the classification of biomedical concepts
Background: Biomedical ontologies are critical for integration of data from diverse sources and for use by knowledge-based biomedical applications, especially natural language pro...
Jung-Wei Fan, Hua Xu, Carol Friedman
BMCBI
2007
159views more  BMCBI 2007»
14 years 14 days ago
Computational genes: a tool for molecular diagnosis and therapy of aberrant mutational phenotype
Background: A finite state machine manipulating information-carrying DNA strands can be used to perform autonomous molecular-scale computations at the cellular level. Results: We ...
Israel Mark Martínez-Pérez, Gong Zha...
BMCBI
2007
79views more  BMCBI 2007»
14 years 14 days ago
Simcluster: clustering enumeration gene expression data on the simplex space
Ricardo Z. N. Vêncio, Leonardo Varuzza, Carl...
BMCBI
2007
194views more  BMCBI 2007»
14 years 14 days ago
A meta-data based method for DNA microarray imputation
Background: DNA microarray experiments are conducted in logical sets, such as time course profiling after a treatment is applied to the samples, or comparisons of the samples unde...
Rebecka Jörnsten, Ming Ouyang, Hui-Yu Wang
BMCBI
2007
113views more  BMCBI 2007»
14 years 14 days ago
Analysis and prediction of antibacterial peptides
Background: Antibacterial peptides are important components of the innate immune system, used by the host to protect itself from different types of pathogenic bacteria. Over the l...
Sneh Lata, B. K. Sharma, G. P. S. Raghava
BMCBI
2007
142views more  BMCBI 2007»
14 years 14 days ago
Predicting and improving the protein sequence alignment quality by support vector regression
Background: For successful protein structure prediction by comparative modeling, in addition to identifying a good template protein with known structure, obtaining an accurate seq...
Minho Lee, Chan-seok Jeong, Dongsup Kim
BMCBI
2007
144views more  BMCBI 2007»
14 years 14 days ago
Spectral estimation in unevenly sampled space of periodically expressed microarray time series data
Background: Periodogram analysis of time-series is widespread in biology. A new challenge for analyzing the microarray time series data is to identify genes that are periodically ...
Alan Wee-Chung Liew, Jun Xian, Shuanhu Wu, David K...
BMCBI
2007
137views more  BMCBI 2007»
14 years 14 days ago
PlnTFDB: an integrative plant transcription factor database
Background: Transcription factors (TFs) are key regulatory proteins that enhance or repress the transcriptional rate of their target genes by binding to specific promoter regions ...
Diego Mauricio Riaño-Pachón, Sloboda...
BMCBI
2007
173views more  BMCBI 2007»
14 years 14 days ago
CGKB: an annotation knowledge base for cowpea (Vigna unguiculata L.) methylation filtered genomic genespace sequences
Background: Cowpea [Vigna unguiculata (L.) Walp.] is one of the most important food and forage legumes in the semiarid tropics because of its ability to tolerate drought and grow ...
Xianfeng Chen, Thomas W. Laudeman, Paul J. Rushton...