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BMCBI
2007
148views more  BMCBI 2007»
14 years 14 days ago
fREDUCE: Detection of degenerate regulatory elements using correlation with expression
Background: The precision of transcriptional regulation is made possible by the specificity of physical interactions between transcription factors and their cognate binding sites ...
Randy Z. Wu, Christina Chaivorapol, Jiashun Zheng,...
BMCBI
2007
71views more  BMCBI 2007»
14 years 14 days ago
Locational distribution of gene functional classes in Arabidopsis thaliana
Michael C. Riley, Amanda Clare, Ross D. King
BMCBI
2007
84views more  BMCBI 2007»
14 years 14 days ago
A comparative study of S/MAR prediction tools
Background: S/MARs are regions of the DNA that are attached to the nuclear matrix. These regions are known to affect substantially the expression of genes. The computer prediction...
Kenneth Evans, Sascha Ott, Annika Hansen, Georgy K...
BMCBI
2007
200views more  BMCBI 2007»
14 years 14 days ago
BNDB - The Biochemical Network Database
Background: Technological advances in high-throughput techniques and efficient data acquisition methods have resulted in a massive amount of life science data. The data is stored ...
Jan Küntzer, Christina Backes, Torsten Blum, ...
BMCBI
2007
77views more  BMCBI 2007»
14 years 14 days ago
Effective selection of informative SNPs and classification on the HapMap genotype data
Background: Since the single nucleotide polymorphisms (SNPs) are genetic variations which determine the difference between any two unrelated individuals, the SNPs can be used to i...
Nina Zhou, Lipo Wang
BMCBI
2007
119views more  BMCBI 2007»
14 years 14 days ago
Efficacy of different protein descriptors in predicting protein functional families
Background: Sequence-derived structural and physicochemical descriptors have frequently been used in machine learning prediction of protein functional families, thus there is a ne...
Serene A. K. Ong, Hong Huang Lin, Yu Zong Chen, Ze...
BMCBI
2007
94views more  BMCBI 2007»
14 years 14 days ago
Model based analysis of real-time PCR data from DNA binding dye protocols
Background: Reverse transcription followed by real-time PCR is widely used for quantification of specific mRNA, and with the use of double-stranded DNA binding dyes it is becoming...
Mariano J. Alvarez, Guillermo J. Vila-Ortiz, Maria...
BMCBI
2007
164views more  BMCBI 2007»
14 years 14 days ago
SEARCHPATTOOL: a new method for mining the most specific frequent patterns for binding sites with application to prokaryotic DNA
Background: Computational methods to predict transcription factor binding sites (TFBS) based on exhaustive algorithms are guaranteed to find the best patterns but are often limite...
Fathi Elloumi, Martha Nason
BMCBI
2007
115views more  BMCBI 2007»
14 years 14 days ago
Correlation between structure and temperature in prokaryotic metabolic networks
Background: In recent years, an extensive characterization of network structures has been made in an effort to elucidate design principles of metabolic networks, providing valuabl...
Kazuhiro Takemoto, Jose C. Nacher, Tatsuya Akutsu