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BMCBI
2007
155views more  BMCBI 2007»
14 years 14 days ago
ProMEX: a mass spectral reference database for proteins and protein phosphorylation sites
Background: In the last decade, techniques were established for the large scale genome-wide analysis of proteins, RNA, and metabolites, and database solutions have been developed ...
Jan Hummel, Michaela Niemann, Stefanie Wienkoop, W...
BMCBI
2007
87views more  BMCBI 2007»
14 years 14 days ago
A manually curated database of tetrapod mitochondrially encoded tRNA sequences and secondary structures
Background: Mitochondrial tRNAs have been the subject of study for structural biologists interested in their secondary structure characteristics, evolutionary biologists have rese...
Konstantin Yu Popadin, Leila A. Mamirova, Fyodor A...
BMCBI
2007
110views more  BMCBI 2007»
14 years 14 days ago
Interpretation of multiple probe sets mapping to the same gene in Affymetrix GeneChips
Background: Affymetrix GeneChip technology enables the parallel observations of tens of thousands of genes. It is important that the probe set annotations are reliable so that bio...
Maria A. Stalteri, Andrew P. Harrison
BMCBI
2007
141views more  BMCBI 2007»
14 years 14 days ago
Artificial neural network models for prediction of intestinal permeability of oligopeptides
Background: Oral delivery is a highly desirable property for candidate drugs under development. Computational modeling could provide a quick and inexpensive way to assess the inte...
Eunkyoung Jung, Junhyoung Kim, Minkyoung Kim, Dong...
BMCBI
2007
101views more  BMCBI 2007»
14 years 14 days ago
Robust detection and verification of linear relationships to generate metabolic networks using estimates of technical errors
Background: The size and magnitude of the metabolome, the ratio between individual metabolites and the response of metabolic networks is controlled by multiple cellular factors. A...
Frank Kose, Jan Budczies, Matthias Holschneider, O...
BMCBI
2007
186views more  BMCBI 2007»
14 years 14 days ago
Modeling human cancer-related regulatory modules by GA-RNN hybrid algorithms
Background: Modeling cancer-related regulatory modules from gene expression profiling of cancer tissues is expected to contribute to our understanding of cancer biology as well as...
Jung-Hsien Chiang, Shih-Yi Chao
BMCBI
2007
120views more  BMCBI 2007»
14 years 14 days ago
Quantitative sequence-function relationships in proteins based on gene ontology
Background: The relationship between divergence of amino-acid sequence and divergence of function among homologous proteins is complex. The assumption that homologs share function...
Vineet Sangar, Daniel J. Blankenberg, Naomi Altman...
BMCBI
2007
217views more  BMCBI 2007»
14 years 14 days ago
OntologyWidget - a reusable, embeddable widget for easily locating ontology terms
Background: Biomedical ontologies are being widely used to annotate biological data in a computer-accessible, consistent and well-defined manner. However, due to their size and co...
Catherine Beauheim, Farrell Wymore, Michael Nitzbe...
BMCBI
2007
86views more  BMCBI 2007»
14 years 14 days ago
Tandem mass spectrometry data quality assessment by self-convolution
Background: Many algorithms have been developed for deciphering the tandem mass spectrometry (MS) data sets. They can be essentially clustered into two classes. The first performs...
Keng Wah Choo, Wai Mun Tham