BMCBI
2007
13 years 7 months ago
2007
BMCBI
2007
13 years 7 months ago
2007
Background: Methods are now available for the prediction of interaction sites in protein 3D structures. While many of these methods report high success rates for site prediction, ...
BMCBI
2007
13 years 7 months ago
2007
Background: Completion of the human genome sequence along with other species allows for greater understanding of the biochemical mechanisms and processes that govern healthy as we...
BMCBI
2007
13 years 7 months ago
2007
Background: Mass spectrometry based peptide mass fingerprints (PMFs) offer a fast, efficient, and robust method for protein identification. A protein is digested (usually by tryps...
BMCBI
2007
13 years 7 months ago
2007
Background: Molecular biologists need sophisticated analytical tools which often demand extensive computational resources. While finding, installing, and using these tools can be ...
BMCBI
2007
13 years 7 months ago
2007
Background: The post-genomic era is characterised by a torrent of biological information flooding the public databases. As a direct consequence, similarity searches starting with ...
BMCBI
2007
13 years 7 months ago
2007
BMCBI
2007
13 years 7 months ago
2007
Background: Sequencing of prokaryotic genomes has recently revealed the presence of CRISPR elements: short, highly conserved repeats separated by unique sequences of similar lengt...
BMCBI
2007
13 years 7 months ago
2007
Background: High-throughput peptide and protein identification technologies have benefited tremendously from strategies based on tandem mass spectrometry (MS/MS) in combination wi...
BMCBI
2007
13 years 7 months ago
2007
Background: In structural genomics, an important goal is the detection and classification of protein–protein interactions, given the structures of the interacting partners. We h...