BMCBI
2007
14 years 21 days ago
2007
Background: The incorporation of prior biological knowledge in the analysis of microarray data has become important in the reconstruction of transcription regulatory networks in a...
BMCBI
2007
14 years 21 days ago
2007
Background: Multiple data-analytic methods have been proposed for evaluating gene-expression levels in specific biological pathways, assessing differential expression associated w...
BMCBI
2007
2007
FUNC: a package for detecting significant associations between gene sets and ontological annotations
14 years 21 days ago
Background: Genome-wide expression, sequence and association studies typically yield large sets of gene candidates, which must then be further analysed and interpreted. Informatio...
BMCBI
2007
14 years 21 days ago
2007
Background: As a consequence of the evolutionary process, data collected from related species tend to be similar. This similarity by descent can obscure subtler signals in the dat...
BMCBI
2007
14 years 21 days ago
2007
Background: Designing appropriate machine learning methods for identifying genes that have a significant discriminating power for disease outcomes has become more and more importa...
BMCBI
2007
14 years 21 days ago
2007
Background: With the explosion in data generated using microarray technology by different investigators working on similar experiments, it is of interest to combine results across...
BMCBI
2007
14 years 21 days ago
2007
Background: In recent years, RNA molecules that are not translated into proteins (ncRNAs) have drawn a great deal of attention, as they were shown to be involved in many cellular ...
BMCBI
2007
14 years 21 days ago
2007
Background: Solenoid repeat proteins of the Tetratrico Peptide Repeat (TPR) family are involved as scaffolds in a broad range of protein-protein interactions. Several resources ar...
BMCBI
2007
14 years 21 days ago
2007
Background: The ability to visualize genomic features and design experimental assays that can target specific regions of a genome is essential for modern biology. To assist in the...
BMCBI
2007
14 years 21 days ago
2007
Background: Many algorithms exist for protein structural alignment, based on internal protein coordinates or on explicit superposition of the structures. These methods are usually...