BMCBI
2007
14 years 20 days ago
2007
Background: The presence of gaps in an alignment of nucleotide or protein sequences is often an inconvenience for bioinformatical studies. In phylogenetic and other analyses, for ...
BMCBI
2007
14 years 20 days ago
2007
Background: Success of metabolomics as the phenotyping platform largely depends on its ability to detect various sources of biological variability. Removal of platform-specific so...
BMCBI
2007
14 years 20 days ago
2007
Background: Several mathematical and statistical methods have been proposed in the last few years to analyze microarray data. Most of those methods involve complicated formulas, a...
BMCBI
2007
14 years 20 days ago
2007
Scientific articles are tailored to present information in human-readable aliquots. Although the Internet has revolutionized the way our society thinks about information, the trad...
BMCBI
2007
14 years 20 days ago
2007
Background: The translational efficiency of an mRNA can be modulated by upstream open reading frames (uORFs) present in certain genes. A uORF can attenuate translation of the main...
BMCBI
2007
14 years 20 days ago
2007
Background: Most human genes produce several transcripts with different exon contents by using alternative promoters, alternative polyadenylation sites and alternative splice site...
BMCBI
2007
14 years 20 days ago
2007
Background: Correct identification of individual Hox proteins is an essential basis for their study in diverse research fields. Common methods to classify Hox proteins focus on th...
BMCBI
2007
14 years 20 days ago
2007
Background: Microarray co-expression signatures are an important tool for studying gene function and relations between genes. In addition to genuine biological co-expression, corr...
BMCBI
2007
14 years 20 days ago
2007
Background: One of the crucial aspects of day-to-day laboratory information management is collection, storage and retrieval of information about research subjects and biomedical s...
BMCBI
2007
14 years 20 days ago
2007
Background: Combinatorial complexity is a challenging problem in detailed and mechanistic mathematical modeling of signal transduction. This subject has been discussed intensively...