BMCBI
2008
13 years 10 months ago
2008
BMCBI
2008
13 years 10 months ago
2008
Background: High-throughput screening of pharmaceutical compound activity in tissue culture experiments requires time-consuming repeated analysis of the large amounts of data gene...
BMCBI
2008
13 years 10 months ago
2008
Background: Survival time is an important clinical trait for many disease studies. Previous works have shown certain relationship between patients' gene expression profiles a...
BMCBI
2008
13 years 10 months ago
2008
Background: Integrating data from multiple global assays and curated databases is essential to understand the spatiotemporal interactions within cells. Different experiments measu...
BMCBI
2008
13 years 10 months ago
2008
Background: The prediction of a consensus structure for a set of related RNAs is an important first step for subsequent analyses. RNAalifold, which computes the minimum energy str...
BMCBI
2008
13 years 10 months ago
2008
Background: Cellular metabolism is one of the most investigated system of biological interactions. While the topological nature of individual reactions and pathways in the network...
BMCBI
2008
13 years 10 months ago
2008
Background: The amount of information stemming from proteomics experiments involving (multi dimensional) separation techniques, mass spectrometric analysis, and computational anal...
BMCBI
2008
13 years 10 months ago
2008
Background: The DNA microarray technology allows the measurement of expression levels of thousands of genes under tens/hundreds of different conditions. In microarray data, genes ...
BMCBI
2008
13 years 10 months ago
2008
Background: Clustering is a popular data exploration technique widely used in microarray data analysis. Most conventional clustering algorithms, however, generate only one set of ...
BMCBI
2008
13 years 10 months ago
2008
Background: The detection of conserved motifs in promoters of orthologous genes (phylogenetic footprints) has become a common strategy to predict cis-acting regulatory elements. S...