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IJBRA
2008
69views more  IJBRA 2008»
13 years 11 months ago
A matrix-based multilevel approach to identify functional protein modules
: Identifying functional modules is believed to reveal most cellular processes. There have been many computational approaches to investigate the underlying biological structures [2...
Suely Oliveira, Sang-Cheol Seok
ALMOB
2006
109views more  ALMOB 2006»
13 years 11 months ago
A novel functional module detection algorithm for protein-protein interaction networks
Background: The sparse connectivity of protein-protein interaction data sets makes identification of functional modules challenging. The purpose of this study is to critically eva...
Woochang Hwang, Young-Rae Cho, Aidong Zhang, Mural...
BMCBI
2007
227views more  BMCBI 2007»
13 years 11 months ago
Growing functional modules from a seed protein via integration of protein interaction and gene expression data
Background: Nowadays modern biology aims at unravelling the strands of complex biological structures such as the protein-protein interaction (PPI) networks. A key concept in the o...
Ioannis A. Maraziotis, Konstantina Dimitrakopoulou...
BMCBI
2007
111views more  BMCBI 2007»
13 years 11 months ago
Modular co-evolution of metabolic networks
Background: The architecture of biological networks has been reported to exhibit high level of modularity, and to some extent, topological modules of networks overlap with known f...
Jing Zhao, Guohui Ding, Lin Tao, Hong Yu, Zhong-Ha...
BMCBI
2010
136views more  BMCBI 2010»
13 years 11 months ago
A hub-attachment based method to detect functional modules from confidence-scored protein interactions and expression profiles
Background: Many research results show that the biological systems are composed of functional modules. Members in the same module usually have common functions. This is useful inf...
Chia-Hao Chin, Shu-Hwa Chen, Chin-Wen Ho, Ming-Tat...
BMCBI
2010
160views more  BMCBI 2010»
13 years 11 months ago
Identification of functional hubs and modules by converting interactome networks into hierarchical ordering of proteins
Background: Protein-protein interactions play a key role in biological processes of proteins within a cell. Recent high-throughput techniques have generated protein-protein intera...
Young-Rae Cho, Aidong Zhang
BIRD
2008
Springer
163views Bioinformatics» more  BIRD 2008»
14 years 1 months ago
Multi-functional Protein Clustering in PPI Networks
Abstract. Protein-Protein Interaction (PPI) networks contain valuable information for the isolation of groups of proteins that participate in the same biological function. Many pro...
Clara Pizzuti, Simona E. Rombo
ITC
2000
IEEE
84views Hardware» more  ITC 2000»
14 years 3 months ago
Non-intrusive BIST for systems-on-a-chip
1 The term "functional BIST" describes a test method to control functional modules so that they generate a deterministic test set, which targets structural faults within ...
Silvia Chiusano, Paolo Prinetto, Hans-Joachim Wund...
COMPLIFE
2005
Springer
14 years 5 months ago
The Architecture of a Proteomic Network in the Yeast
Abstract. We describe an approach to clustering the yeast protein-protein interaction network in order to identify functional modules, groups of proteins forming multi-protein comp...
Emad Ramadan, Christopher Osgood, Alex Pothen