T1DBase (http://www.t1dbase.org) is web platform, which supports the type 1 diabetes (T1D) community. It integrates genetic, genomic and expression data relevant to T1D research a...
Oliver S. Burren, Ellen C. Adlem, Premanand Achuth...
Background: In genetic transcription research, gene expression is typically reported in a test sample relative to a reference sample. Laboratory assays that measure gene expressio...
Modern biology has moved from a science of individual measurements to a science where data are collected on an industrial scale. Foremost, among the new tools for biochemistry are ...
William B. Langdon, Graham J. G. Upton, Renata da ...
Background: Circadian rhythms are 24 hour oscillations in many behavioural, physiological, cellular and molecular processes that are controlled by an endogenous clock which is ent...
Meric A. Ovacik, Siddharth Sukumaran, Richard R. A...
Microarray technologies have allowed the measurement of expression of multiple genes simultaneously. Gene expression levels can be used to classify tissues into diagnostic or progn...
Lucila Ohno-Machado, Staal A. Vinterbo, Griffin We...
Background: The detection of small yet statistically significant differences in gene expression in spotted DNA microarray studies is an ongoing challenge. Meeting this challenge r...
Background: There are a number of methods (also called: measures) currently in use that quantify codon usage in genes. These measures are often influenced by other sequence proper...
Background: As genomes evolve after speciation, gene content, coding sequence, gene expression, and splicing all diverge with time from ancestors with close relatives. A minimum e...
Roald Rossnes, Ingvar Eidhammer, David A. Liberles
Background: The Affymetrix™ technology is nowadays a well-established method for the analysis of gene expression profiles in cancer research studies. However, changes in gene ex...
Davide Rambaldi, Barbara Felice, Viviane Praz, Phi...
Background: This work explores the quantitative characteristics of the local transcriptional regulatory network based on the availability of time dependent gene expression data se...