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BMCBI
2010
97views more  BMCBI 2010»
13 years 6 months ago
A semi-parametric Bayesian model for unsupervised differential co-expression analysis
Background: Differential co-expression analysis is an emerging strategy for characterizing disease related dysregulation of gene expression regulatory networks. Given pre-defined ...
Johannes M. Freudenberg, Siva Sivaganesan, Michael...
GPB
2010
231views Solid Modeling» more  GPB 2010»
13 years 8 months ago
Mining Gene Expression Profiles: An Integrated Implementation of Kernel Principal Component Analysis and Singular Value Decompos
The detection of genes that show similar profiles under different experimental conditions is often an initial step in inferring the biological significance of such genes. Visualiz...
Ferran Reverter, Esteban Vegas, Pedro Sánch...
ENTCS
2010
97views more  ENTCS 2010»
13 years 8 months ago
A Framework for Modelling and Simulating Networks of Cells
Several complex biological phenomena are to be modelled in terms of a large and dynamic network of compartments, where the interplay between inter-compartment and intra-compartmen...
Sara Montagna, Mirko Viroli
BMCBI
2010
183views more  BMCBI 2010»
13 years 8 months ago
The complexity of gene expression dynamics revealed by permutation entropy
Background: High complexity is considered a hallmark of living systems. Here we investigate the complexity of temporal gene expression patterns using the concept of Permutation En...
Xiaoliang Sun, Yong Zou, Victoria J. Nikiforova, J...
BMCBI
2010
196views more  BMCBI 2010»
13 years 8 months ago
Content-based microarray search using differential expression profiles
Background: With the expansion of public repositories such as the Gene Expression Omnibus (GEO), we are rapidly cataloging cellular transcriptional responses to diverse experiment...
Jesse M. Engreitz, Alexander A. Morgan, Joel Dudle...
AISS
2010
120views more  AISS 2010»
13 years 9 months ago
An Integrated Analysis System for Agricultural Biotechnology Information and Web Service
The National Agricultural Biotechnology Information Center (NABIC) constructs an agricultural biology-based infrastructure and develops a biotechnological database. The NABIC has ...
ChangKug Kim, UngHan Yoon, GangSeob Lee, DoWon Yun...
ICMLA
2010
13 years 9 months ago
Smoothing Gene Expression Using Biological Networks
Gene expression (microarray) data have been used widely in bioinformatics. The expression data of a large number of genes from small numbers of subjects are used to identify inform...
Yue Fan, Mark A. Kon, Shinuk Kim, Charles DeLisi
GCB
2010
Springer
204views Biometrics» more  GCB 2010»
13 years 9 months ago
Learning Pathway-based Decision Rules to Classify Microarray Cancer Samples
: Despite recent advances in DNA chip technology current microarray gene expression studies are still affected by high noise levels, small sample sizes and large numbers of uninfor...
Enrico Glaab, Jonathan M. Garibaldi, Natalio Krasn...
TCBB
2010
136views more  TCBB 2010»
13 years 9 months ago
Integrating Data Clustering and Visualization for the Analysis of 3D Gene Expression Data
— The recent development of methods for extracting precise measurements of spatial gene expression patterns from three-dimensional (3D) image data opens the way for new analyses ...
Oliver Rübel, Gunther H. Weber, Min-Yu Huang,...
PRL
2007
98views more  PRL 2007»
13 years 11 months ago
Error probabilities for local extrema in gene expression data
Current approaches for the prediction of functional relations from gene expression data often do not have a clear methodology for extracting features and are not accompanied by a ...
Perry Groot, Christian Gilissen, Michael Egmont-Pe...