RECOMB
2011
Springer
13 years 3 months ago
2011
Springer
Abstract. Haplotypes, as they specify the linkage patterns between dispersed genetic variations, provide important information for understanding the genetics of human traits. Howev...
BMCBI
2011
13 years 7 months ago
2011
Background: Recently we have witnessed a surge of interest in using genome-wide association studies (GWAS) to discover the genetic basis of complex diseases. Many genetic variatio...
NAR
2011
13 years 7 months ago
2011
Numerous genetic variations have been found to be related to human diseases. Significant portion of those affect the drug response as well by changing the protein structure and fu...
ISAMI
2010
13 years 10 months ago
2010
It is widely agreed that complex diseases are typically caused by the joint effects of multiple instead of a single genetic variation. These genetic variations may show very little...
BMCBI
2007
14 years 17 days ago
2007
Background: Human genetic variations primarily result from single nucleotide polymorphisms (SNPs) that occur approximately every 1000 bases in the overall human population. The no...
BMCBI
2010
14 years 20 days ago
2010
Background: Obesity is a multifactorial trait, which comprises an independent risk factor for cardiovascular disease (CVD). The aim of the current work is to study the complex eti...
CSB
2003
IEEE
14 years 5 months ago
2003
IEEE
The promise of plentiful data on common human genetic variations has given hope that we will be able to uncover genetic factors behind common diseases that have proven difficult ...