BMCBI
2008
14 years 17 days ago
2008
Background: Structural similarities among proteins can provide valuable insight into their functional mechanisms and relationships. As the number of available three-dimensional (3...
BMCBI
2010
14 years 17 days ago
2010
Background: Folding of a protein into its three dimensional structure is influenced by both local and global interactions within a protein. Higher order residue interactions, like...
BMCBI
2010
14 years 17 days ago
2010
Background: Protein structure comparison is a fundamental task in structural biology. While the number of known protein structures has grown rapidly over the last decade, searchin...
BMCBI
2010
14 years 17 days ago
2010
Background: The current advances in electron cryo-microscopy technique have made it possible to obtain protein density maps at about 6-10
BMCBI
2010
14 years 17 days ago
2010
Background: Recombinant protein production is a useful biotechnology to produce a large quantity of highly soluble proteins. Currently, the most widely used production system is t...
BMCBI
2010
14 years 17 days ago
2010
Background: Post-translational modifications (PTMs) have a key role in regulating cell functions. Consequently, identification of PTM sites has a significant impact on understandi...
BMCBI
2010
14 years 17 days ago
2010
Background: Prediction of protein localization in subnuclear organelles is more challenging than general protein subcelluar localization. There are only three computational models...
BMCBI
2010
14 years 17 days ago
2010
Background: Phosphorylation events direct the flow of signals and metabolites along cellular protein networks. Current annotations of kinase-substrate binding events are far from ...
BMCBI
2010
14 years 17 days ago
2010
Background: Efficient dissection of large proteins into their structural domains is critical for high throughput proteome analysis. So far, no study has focused on mathematically ...
BMCBI
2010
14 years 17 days ago
2010
Background: Guanosine triphosphate (GTP)-binding proteins play an important role in regulation of G-protein. Thus prediction of GTP interacting residues in a protein is one of the...