We consider the problem of finding similarities in protein structure databases. Our techniques extract feature vectors on triplets of SSEs (Secondary Structure Elements). Later, ...
Protein interactions typically arise from a physical interaction of one or more small sites on the surface of the two proteins. Identifying these sites is very important for drug ...
Haidong Wang, Eran Segal, Asa Ben-Hur, Daphne Koll...
Predicting protein secondary structure is a key step in determining the 3D structure of a protein that determines its function. The Dictionary of Secondary Structure of Proteins (...
- The search for structural similarity among proteins can provide valuable insights into their functional mechanisms and their functional relationships. Though the protein 1D seque...
Most proteins function only when folded into a particular 3D configuration. Recently, a class of proteins has been discovered that do not fold into any particular configuration; t...
Here we investigate an extension of a previously suggested "automatic amide I frequency selection procedure" where we introduce an additional criterion utilizing empiric...
Joachim A. Hering, Peter R. Innocent, Parvez I. Ha...
- Integrating information about protein sequence and structure allows further exploration and establishment of protein sequence-structure-function relations. However, protein data ...
The classification of proteins based on their structure can play an important role in the deduction or discovery of protein function. However, the relatively low number of solved...
Keith Marsolo, Srinivasan Parthasarathy, Chris H. ...
Protein domains are the building blocks of proteins, and their interactions are crucial in forming stable protein-protein interactions (PPI) and take part in many cellular processe...
To cope with the large amount of biological sequences being produced, a significant number of genes and proteins have been annotated by automated tools. A protein annotation is an...