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BMCBI
2010
86views more  BMCBI 2010»
14 years 17 days ago
Mining protein loops using a structural alphabet and statistical exceptionality
Background: Protein loops encompass 50% of protein residues in available three-dimensional structures. These regions are often involved in protein functions, e.g. binding site, ca...
Leslie Regad, Juliette Martin, Grégory Nuel...
BIOINFORMATICS
2007
161views more  BIOINFORMATICS 2007»
14 years 17 days ago
Functional evaluation of domain-domain interactions and human protein interaction networks
: Large amounts of protein and domain interaction data are being produced by experimental high-throughput techniques and computational approaches. To gain insight into the value of...
Andreas Schlicker, Carola Huthmacher, Fidel Ram&ia...
BIB
2007
82views more  BIB 2007»
14 years 17 days ago
High-throughput modeling and analysis of protein structural dynamics
Protein function is a dynamic property closely related to the conformational mechanisms of protein structure in its physiological environment. To understand and control the functi...
Xiong Liu, Hassan A. Karimi
AROBOTS
2007
81views more  AROBOTS 2007»
14 years 17 days ago
Mobile robot team forming for crystallization of proteins
The process of protein crystallization is explained using the theory of robotics, particularly path planning of mobile robots. Path planning is a procedure which specifies motion ...
Yuan F. Zheng, Weidong Chen
BIBE
2007
IEEE
152views Bioinformatics» more  BIBE 2007»
14 years 18 days ago
SBLAST: Structural Basic Local Alignment Searching Tools using Geometric Hashing
While much research has been done on finding similarities between protein sequences, there has not been the same progress on finding similarities between protein structures. Here ...
Tom Milledge, Gaolin Zheng, Tim Mullins, Giri Nara...
HPDC
2010
IEEE
14 years 1 months ago
Modeling sequence and function similarity between proteins for protein functional annotation
A common task in biological research is to predict function for proteins by comparing sequences between proteins of known and unknown function. This is often done using pair-wise ...
Roger Higdon, Brenton Louie, Eugene Kolker
ISMB
1993
14 years 1 months ago
A Modular Learning Environment for Protein Modeling
Wepropose in this paper a modularlearning environmentfor proteinmodeling.In this system,the protein modelingproblemis tackledin twosuccessive phases. First, partial structural inf...
Jérôme Gracy, Laurent Chiche, Jean Sa...
ISMB
1994
14 years 1 months ago
Stochastic Motif Extraction Using Hidden Markov Model
In this paper, westudy the application of an ttMM(hidden Markov model) to the problem of representing protein sequencesby a stochastic motif. Astochastic protein motif represents ...
Yukiko Fujiwara, Minoru Asogawa, Akihiko Konagaya
ISMB
1997
14 years 1 months ago
Hierarchical Protein Structure Superposition Using Both Secondary Structure and Atomic Representations
The structural comparison of proteins has become increasingly important as a means to identify protein motifs and fold families. In this paper we present a new algorithm for the c...
Amit Pal Singh, Douglas L. Brutlag
ISMB
2000
14 years 1 months ago
Towards a Systematics for Protein Subcellular Location: Quantitative Description of Protein Localization Patterns and Automated
Determination of the functions of all expressed proteins represents one of the major upcoming challenges in computational molecular biology. Since subcellular location plays a cru...
Robert F. Murphy, Michael V. Boland, Meel Velliste