Abstract-Post-translational protein modifications play an important role in many protein pathways and interactions. It has been hypothesized that modifications to proteins occur in...
— Proteins have been discovered to contain ordered regions and disordered regions, where ordered regions have a defined three-dimensional (3D) structure and disordered regions d...
Searching bio-chemical structures is becoming an important application domain of information retrieval. This paper introduces a protein structure matching problem and formulates i...
—Homology modeling requires an accurate alignment between a query sequence and its homologs with known three-dimensional (3D) information. Current structural modeling techniques ...
Abstract–Protein families can be used to reconstruct evolutionary histories of organisms. The accuracy of protein assignment to such families is critical for the success of such ...
Boris Mirkin, Renata da Silva Camargo, Trevor I. F...
Although snake venom proteins have been proven instrumental in the design of blood clotting and cytostatic breast cancer drugs, the main method in use to sequence these unknown pr...
Two-dimensional gel electrophoresis (2DGE) is a technique to separate individual proteins in biological samples. The 2DGE technique results in gel images where proteins appear as d...
Ji Won Yoon, Simon J. Godsill, ChulHun Kang, Tae-S...
The coiled-coil protein domain is a widespread structural motif known to be involved in a wealth of key interactions in cells and organisms. Coiled-coil recognition and prediction ...
Three strategies are presented for developing a knowledge-based statistical contact potential from computationally hydrated proteins that may be useful in studies of protein foldi...
Structural biology research places significant demands upon computing and informatics infrastructure. Protein production, crystallization and X-ray data collection require solutio...
Noel G. Faux, Anthony Beitz, Mark A. Bate, Abdulla...