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BMCBI
2010
145views more  BMCBI 2010»
13 years 11 months ago
Clustering metagenomic sequences with interpolated Markov models
Background: Sequencing of environmental DNA (often called metagenomics) has shown tremendous potential to uncover the vast number of unknown microbes that cannot be cultured and s...
David R. Kelley, Steven L. Salzberg
BMCBI
2010
82views more  BMCBI 2010»
13 years 11 months ago
SolexaQA: At-a-glance quality assessment of Illumina second-generation sequencing data
Background: Illumina's second-generation sequencing platform is playing an increasingly prominent role in modern DNA and RNA sequencing efforts. However, rapid, simple, stand...
Murray P. Cox, Daniel A. Peterson, Patrick J. Bigg...
BMCBI
2010
144views more  BMCBI 2010»
13 years 11 months ago
Graph-based clustering and characterization of repetitive sequences in next-generation sequencing data
Background: The investigation of plant genome structure and evolution requires comprehensive characterization of repetitive sequences that make up the majority of higher plant nuc...
Petr Novák, Pavel Neumann, Jirí Maca...
BMCBI
2010
120views more  BMCBI 2010»
13 years 11 months ago
Short clones or long clones? A simulation study on the use of paired reads in metagenomics
Background: Metagenomics is the study of environmental samples using sequencing. Rapid advances in sequencing technology are fueling a vast increase in the number and scope of met...
Suparna Mitra, Max Schubach, Daniel H. Huson
BMCBI
2010
133views more  BMCBI 2010»
13 years 11 months ago
Improving de novo sequence assembly using machine learning and comparative genomics for overlap correction
Background: With the rapid expansion of DNA sequencing databases, it is now feasible to identify relevant information from prior sequencing projects and completed genomes and appl...
Lance E. Palmer, Mathäus Dejori, Randall A. B...
BMCBI
2010
156views more  BMCBI 2010»
13 years 11 months ago
Evaluation of statistical methods for normalization and differential expression in mRNA-Seq experiments
Background: High-throughput sequencing technologies, such as the Illumina Genome Analyzer, are powerful new tools for investigating a wide range of biological and medical question...
James H. Bullard, Elizabeth Purdom, Kasper D. Hans...
GECCO
2008
Springer
145views Optimization» more  GECCO 2008»
14 years 18 days ago
An evolutionary approach for competency-based curriculum sequencing
The process of creating e-learning contents using reusable learning objects (LOs) can be broken down in two sub-processes: LOs finding and LO sequencing. Sequencing is usually per...
Luis de Marcos, José-Javier Martínez...
METMBS
2004
162views Mathematics» more  METMBS 2004»
14 years 27 days ago
A Comparison of DNA Fragment Assembly Algorithms
As more research centers embark on sequencing new genomes, the problem of DNA fragment assembly for shotgun sequencing is growing in importance and complexity. Accurate and fast a...
Lishan Li, Sami Khuri
IADIS
2004
14 years 27 days ago
Constructing Scorm Compliant Course Based on High Level Petri Nets
With rapid development of the Internet, e-learning system has become more and more popular. Currently, to solve the issue of sharing and reusing of teaching materials in different...
Jun-Ming Su, Shian-Shyong Tseng, Chia-Yu Chen, Jui...
FOCS
1995
IEEE
14 years 3 months ago
Reconstructing Strings from Substrings in Rounds
We establish a variety of combinatorial bounds on the tradeo s inherent in reconstructing strings using few rounds of a given number of substring queries per round. These results ...
Dimitris Margaritis, Steven Skiena