Background: Intracellular signal transduction is achieved by networks of proteins and small molecules that transmit information from the cell surface to the nucleus, where they ul...
Martin Steffen, Allegra Petti, John Aach, Patrik D...
Background: Using microarray and sequencing platforms, a large number of copy number variations (CNVs) have been identified in humans. In practice, because our human genome is a d...
The analysis of genetic diseases has classically been directed towards establishing direct links between cause, a genetic variation, and effect, the observable deviation of phenot...
Benjamin Georgi, M. Anne Spence, Pamela Flodman, A...
Background: This work explores the quantitative characteristics of the local transcriptional regulatory network based on the availability of time dependent gene expression data se...
Although microarrays are already having a tremendous impact on biomedical science, they still present great computational challenges. We examine a particular problem involving the...
Tom Van Court, Martin C. Herbordt, Richard J. Bart...