DNA microarrays are a valuable tool for massively parallel DNA-DNA hybridization experiments. Currently, most applications rely on the existence of sequence-specific oligonucleot...
Large-scale comparison of genomic DNA is of fundamental importance in annotating functional elements of genomes. To perform large comparisons efficiently, BLAST (Methods: Companio...
This paper presents the Smith and Waterman Algorithm-Specific ASIC Design (SWASAD) project. This is a hardware solution that implements the S&W algorithm.. The SWASAD is an imp...
Sequence design is a crucial problem in information-based biotechnology such as DNA-based computation. We introduce a simple strategy named template method that systematically gene...
Our group has recently developed a compact, universal protein binding microarray (PBM) that can be used to determine the binding preferences of transcription factors (TFs) [1]. Thi...
Anthony A. Philippakis, Aaron M. Qureshi, Michael ...