Information technology research has played a significant role in the high-throughput acquisition and analysis of biological information. The tremendous amount of information gath...
Protein Data Integration approaches at the moment considers data sources as data repositories, but not as applications; which in turn may embody complex interactions with other da...
Amandeep S. Sidhu, Tharam S. Dillon, Elizabeth Cha...
In the initial stage of sequence analysis, a biologist is first faced with the questions about how to choose the best tool to align sequences of interest and how to analyze and v...
Arthur Chun-Chieh Shih, D. T. Lee, Laurent Lin, Ch...
Experimental processes to collect and process proteomics data are increasingly complex, while the computational methods to assess the quality and significance of these data remain...
Perhaps the most common question that a microarray study can ask is, “Between two given biological conditions, which genes exhibit changed expression levels?” Existing methods...
Will Sheffler, Eli Upfal, John Sedivy, William Sta...
We study the parsimony approach to haplotype inference, which calls for finding a set of haplotypes of minimum cardinality that explains an input set of genotypes. We prove that ...
We present a software package which can detect homozygous SNPs and indels on a eukaryotic genome scale from millions of shotgun reads. Matching seeds of a few kmer words are found...
A linear programming algorithm is presented to constructively compute thermodynamically feasible fluxes and change in chemical potentials of reactions for a metabolic network. It...