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CIBCB
2007
IEEE
13 years 11 months ago
Prediction of Enzyme Catalytic Sites from Sequence Using Neural Networks
The accurate prediction of enzyme catalytic sites remains an open problem in bioinformatics. Recently, several structure-based methods have become popular; however, few robust seq...
Swati Pande, Amar Raheja, Dennis R. Livesay
CIBCB
2007
IEEE
13 years 11 months ago
Genetic Regulatory Network Modeling Using Network Component Analysis and Fuzzy Clustering
Gene regulatory network model is the most widely used mechanism to model and predict the behavior of living organisms. Network Component Analysis (NCA) as an emerging issue for unc...
Fatemeh Bakouie, Mohammad Hassan Moradi
CIBCB
2007
IEEE
13 years 11 months ago
Associative Artificial Neural Network for Discovery of Highly Correlated Gene Groups Based on Gene Ontology and Gene Expression
Abstract-- The advance of high-throughput experimental technologies poses continuous challenges to computational data analysis in functional and comparative genomics studies. Gene ...
Ji He, Xinbin Dai, Xuechun Zhao
BICOB
2009
Springer
13 years 11 months ago
Constrained Fisher Scores Derived from Interaction Profile Hidden Markov Models Improve Protein to Protein Interaction Predictio
Protein-protein interaction plays critical roles in cellular functions. In this work, we propose a computational method to predict protein-protein interaction by using support vec...
Alvaro J. González, Li Liao
AB
2007
Springer
13 years 11 months ago
Reduction of Algebraic Parametric Systems by Rectification of Their Affine Expanded Lie Symmetries
Lie group theory states that knowledge of a m-parameters solvable group of symmetries of a system of ordinary differential equations allows to reduce by m the number of equations. ...
Alexandre Sedoglavic
AB
2007
Springer
13 years 11 months ago
Prefix Reversals on Binary and Ternary Strings
Given a permutation , the application of prefix reversal f(i) to reverses the order of the first i elements of . The problem of Sorting By Prefix Reversals (also known as pancake ...
Cor A. J. Hurkens, Leo van Iersel, Judith Keijsper...
AB
2007
Springer
13 years 11 months ago
Efficient Haplotype Inference with Pseudo-boolean Optimization
Abstract. Haplotype inference from genotype data is a key computational problem in bioinformatics, since retrieving directly haplotype information from DNA samples is not feasible ...
Ana Graça, João Marques-Silva, In&ec...
EBERNBURG
1990
13 years 11 months ago
Problems of Autonomy and Discontexturality in the Theory of Living Systems
In the theory of living systems any description of self-organizing processes is confronted by a very central problem concerning the role of the system's boundary, i.e., there...
Rudolf Kaehr, E. von Goldammer
RECOMB
1997
Springer
13 years 11 months ago
A more efficient approximation scheme for tree alignment
We present a new polynomial time approximation scheme (PTAS) for tree alignment, which is an important variant of multiple sequence alignment. As in the existing PTASs in the liter...
Lusheng Wang, Tao Jiang, Dan Gusfield
RECOMB
1997
Springer
13 years 11 months ago
Pooling strategies for establishing physical genome maps using FISH
Fengzhu Sun, Gary Benson, Norman Arnheim, Michael ...