Sciweavers

RECOMB
2004
Springer
14 years 12 months ago
Learning Regulatory Network Models that Represent Regulator States and Roles
Abstract. We present an approach to inferring probabilistic models of generegulatory networks that is intended to provide a more mechanistic representation of transcriptional regul...
Keith Noto, Mark Craven
RECOMB
2004
Springer
14 years 12 months ago
Predicting Genetic Regulatory Response Using Classification: Yeast Stress Response
We present a novel classification-based algorithm called GeneClass for learning to predict gene regulatory response. Our approach is motivated by the hypothesis that in simple orga...
Manuel Middendorf, Anshul Kundaje, Chris Wiggins, ...
RECOMB
2004
Springer
14 years 12 months ago
Modeling and Analysis of Heterogeneous Regulation in Biological Networks
Abstract. In this study we propose a novel model for the representation of biological networks and provide algorithms for learning model parameters from experimental data. Our appr...
Irit Gat-Viks, Amos Tanay, Ron Shamir
RECOMB
2004
Springer
14 years 12 months ago
Finding short DNA motifs using permuted markov models
Xiaoyue Zhao, Haiyan Huang, Terence P. Speed
RECOMB
2004
Springer
14 years 12 months ago
Finding approximate tandem repeats in genomic sequences
An efficient algorithm is presented for detecting approximate tandem repeats in genomic sequences. The algorithm is based on a flexible statistical model which allows a wide range...
Ydo Wexler, Zohar Yakhini, Yechezkel Kashi, Dan Ge...
RECOMB
2004
Springer
14 years 12 months ago
Using motion planning to study RNA folding kinetics
We propose a novel, motion planning based approach to approximately map the energy landscape of an RNA molecule. Our method is based on the successful probabilistic roadmap motion...
Xinyu Tang, Bonnie Kirkpatrick, Shawna L. Thomas, ...
RECOMB
2004
Springer
14 years 12 months ago
Designing multiple simultaneous seeds for DNA similarity search
The challenge of similarity search in massive DNA sequence databases has inspired major changes in BLAST-style alignment tools, which accelerate search by inspecting only pairs of...
Yanni Sun, Jeremy Buhler
RECOMB
2004
Springer
14 years 12 months ago
Computational identification of evolutionarily conserved exons
Phylogenetic hidden Markov models (phylo-HMMs) have recently been proposed as a means for addressing a multispecies version of the ab initio gene prediction problem. These models ...
Adam C. Siepel, David Haussler
RECOMB
2004
Springer
14 years 12 months ago
A discriminative model for identifying spatial cis-regulatory modules
Transcriptional regulation is mediated by the coordinated binding of transcription factors to the upstream regions of genes. In higher eukaryotes, the binding sites of cooperating...
Eran Segal, Roded Sharan